Results 161 to 170 of about 11,435,493 (279)

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, Volume 13, Issue 53, 24 September 2026.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Protective Effect of Calcitonin Gene-Related Peptide on Corneal Epithelial Barrier in Experimental Dry Eye Models. [PDF]

Invest Ophthalmol Vis Sci
Shi J, He H, Liu A, He W, Yan H, Liao Y, Li W, Wu H, Zong R, Yin J, Lin Z.   +10 more
europepmc   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, Volume 13, Issue 53, 24 September 2026.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

Calcitonin gene-related peptide as a neuroimmune amplifier in allergic rhinitis: from disease worsening to targeted drug intervention. [PDF]

Front Immunol
Qubi Y, Zhou Y, Wang H, Mao Y, Qiu B, Liu Z, Du X, Xu Y, Wu M.   +8 more
europepmc   +1 more source

Lidocaine Combined With Platelet‐Rich Plasma for Stellate Ganglion Block in Chronic Migraine: A Multicenter, Prospective, Propensity Score‐Matched Cohort Study

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objectives To explore the association of stellate ganglion block with platelet‐rich plasma plus lidocaine with clinical outcomes in adults with chronic migraine, in comparison to lidocaine alone. Methods This multicenter prospective exploratory study enrolled 200 adults with chronic migraine scheduled for stellate ganglion block across three ...
Lu Liu, Baolin Duan, Tao Ma, Long Li, Dong Yang, Fang Luo   +5 more
wiley   +1 more source

Schwann Cells in Physical Nerve Injury and Tumor Perineural Invasion: A Functional Overview and Comparison

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT The nervous system exhibits remarkable stability, making its repair challenging. Compared to the central nervous system, peripheral nerve injuries demonstrate a greater potential for regeneration. Schwann cells, the unique myelinating glial cells of the peripheral nervous system, possess striking plasticity and support nerve regeneration ...
Yanni Zheng, Xin Chen, Jiachen Liu, Jiayi Chen, Lei Tang, Wenjun Liu, Yuxin Lin, Xuedong Wei   +7 more
wiley   +1 more source

Calcitonin Gene-Related Peptide (CGRP): Biology, Signaling, Pathophysiological Roles, and Therapeutic Applications. [PDF]

Int J Mol Sci
Ramírez-Expósito MJ, Cueto-Ureña C, Martínez-Martos JM.   +2 more
europepmc   +1 more source

Smoking Abstinence Elicits Hyperalgesia: Neural Mechanism, Clinical Implications, and Pharmacological Managements

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The cycle between nicotine use and pain modulation. Cigarette smoking leads to nicotine entering the body, which binds to nicotinic acetylcholine receptors (nAChRs) in the brain, triggering the release of different neurotransmitters, including dopamine (DA), norepinephrine (NE), serotonin (5‐HT), and GABA.
Shan‐shan Hu, Chao‐feng Zhang, Battuvshin Lkhagvasuren, Di Wang   +3 more
wiley   +1 more source

Cancer‐related pain: A bidirectional modulator of cancer progression

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He, Yu Zhang, Qian Liu, Biao Yan, Peiwei Chai, Renbing Jia   +5 more
wiley   +1 more source