Results 151 to 160 of about 13,600,961 (272)

The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 10, Page 977-992, December 2026.
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario   +3 more
wiley   +1 more source

Peptide‐Linked Bivalent Nanobody Constructs as Positive Allosteric Modulators of the Calcium‐Sensing Receptor

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT We previously developed nanobodies acting as positive allosteric modulators (PAMs) of the calcium‐sensing receptor (CaSR). Here, we sought to develop more potent CaSR modulators by creating bivalent nanobody constructs using ‘tail‐to‐head’ peptide‐linker conjugation.
Mahdis Nabipour   +5 more
wiley   +1 more source

Calcitonin gene-related peptide induces headache attacks in people with idiopathic intracranial hypertension. [PDF]

open access: yesBrain
Yiangou A   +10 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, Volume 20, Issue 11, Page 2569-2583, November 2026.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

open access: yesAnnals of Neurology, Volume 100, Issue 5, Page 915-930, November 2026.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini   +4 more
wiley   +1 more source

Trigeminovascular calcitonin gene-related peptide release and peripheral vascular responses in a mouse model of accelerated aging: Implications for migraine. [PDF]

open access: yesJ Headache Pain
Al-Hassany L   +6 more
europepmc   +2 more sources

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