The use of triptans, opioids, and other rescue medications among patients with migraine prescribed calcitonin gene-related peptide inhibitors for migraine prophylaxis. [PDF]
Nguyen JL +6 more
europepmc +1 more source
The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario +3 more
wiley +1 more source
Calcitonin Gene-Related Peptide Signalling in Alcohol Use Disorders: A Scoping Review. [PDF]
Pellesi L, Ahmad TA, Guerzoni S.
europepmc +1 more source
ABSTRACT We previously developed nanobodies acting as positive allosteric modulators (PAMs) of the calcium‐sensing receptor (CaSR). Here, we sought to develop more potent CaSR modulators by creating bivalent nanobody constructs using ‘tail‐to‐head’ peptide‐linker conjugation.
Mahdis Nabipour +5 more
wiley +1 more source
Calcitonin gene-related peptide induces headache attacks in people with idiopathic intracranial hypertension. [PDF]
Yiangou A +10 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Online interest in calcitonin gene-related peptide-therapies: An infodemiology study using Google trends. [PDF]
Ong B +5 more
europepmc +1 more source
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini +4 more
wiley +1 more source
Trigeminovascular calcitonin gene-related peptide release and peripheral vascular responses in a mouse model of accelerated aging: Implications for migraine. [PDF]
Al-Hassany L +6 more
europepmc +2 more sources
Tear fluid Calcitonin gene-related peptide in patients with idiopathic intracranial hypertension headache - a prospective case-control study. [PDF]
Thunstedt C +5 more
europepmc +1 more source

