Results 131 to 140 of about 36,287 (271)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Safety and tolerability of atogepant for the preventive treatment of migraine: a post hoc analysis of pooled data from four clinical trials

The Journal of Headache and Pain
Background Conventional, non-specific preventive migraine treatments often demonstrate low rates of treatment persistence due to poor efficacy or tolerability.
Paul Rizzoli, Michael J. Marmura, Jennifer Robblee, Jennifer McVige, Sara Sacco, Stephanie J. Nahas, Jessica Ailani, Rosa De Abreu Ferreira, Julia Ma, Jonathan H. Smith, Brett Dabruzzo, Messoud Ashina   +11 more
doaj   +1 more source

Lipoxygenase-derived eicosanoids in myocardial ischaemia-reperfusion injury: the role of sensory C-fibres and TRPV1

, 2010
PhDIt is well established that the 12-lipoxygenase (12-LOX) pathway of arachidonic acid (AA) metabolism is stimulated within the myocardium by episodes of ischaemia, and there is considerable evidence showing that eicosanoids derived via this pathway ...
Goddard, Alison
core  

Calcitonin gene–related peptide enhances the recovery of contractile function in stunned myocardium

, 2000
Introduction: Calcitonin gene-related peptide, a potent vasodilating inotropic agent, increases coronary artery perfusion when administered exogenously and reduces ischemic injury in nonmyocardial tissue.
Glower, D D, Atkins, B.Zane, Silvestry, Scott C., Sabiston, David C., Atkins, B Z, Shah, Ashish S., Samy, Ravi N, MD, Glower, Donald D., Silvestry, S C, Samy, Ravi N., Shah, A S, Sabiston, D C   +11 more
core   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Calcitonin gene related peptide

Inpharma Weekly, 1991
D J, O'Halloran, S R, Bloom
openaire   +4 more sources

Editorial: Calcitonin Gene-Related Peptide: Novel Biology and Treatments

Frontiers in Physiology, 2022
Susan D. Brain, Andrew F. Russo, Andrew F. Russo, Andrew F. Russo, Debbie L. Hay   +4 more
doaj   +1 more source

Efficacy and safety of rimegepant in Chinese women with pure menstrual migraine: a retrospective observational study

BMC Neurology
Objective To evaluate rimegepant’s effectiveness and safety in the short-term prevention of pure menstrual migraine. Background Rimegepant’s effectiveness and safety in both acute and preventive treatment of migraine have been demonstrated by numerous ...
Wenlu Ye, Yongli Fan, Jia Liu, Xuan Xu, Xing Xu, Dan Li, Juan Liu, Yixian Huang   +7 more
doaj   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, EarlyView.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Calcitonin gene-related peptide reduces brain injury in a rat model of focal cerebral ischemia.

, 1994
Calcitonin gene-related peptide is an endogenous vasodilating neuropeptide with a dense concentration in the trigeminocerebrovascular system. It is hypothesized that depletion of this peptide contributes to delayed cerebral ischemia after subarachnoid ...
B A Bell, W A Taylor, J P Holland, S G Sydserff   +3 more
core   +1 more source