Results 111 to 120 of about 13,600,961 (272)

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

Calcitonin gene-related peptide induced migraine attacks in patients with and without familial aggregation of migraine

, 2017
Background Calcitonin gene-related peptide provokes migraine attacks in 65% of patients with migraine without aura. Whether aggregation of migraine in first-degree relatives (family load) or a high number of risk-conferring single nucleotide ...
Christensen, Anne Francke, Janjooa, Benjamin Naveed, Ashina, Messoud, Olesen, Jes, Guo, Song, Liu, Marie Louise   +5 more
core   +1 more source

Subspecialty headache clinic visit reduced healthcare utilization in patients with migraine: Single institution retrospective cohort study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to evaluate whether care in a subspecialty headache center, compared with a general neurology clinic, was associated with lower 90‐day unplanned healthcare utilization (HCU) in patients with migraine and to identify patient‐level factors associated with higher unplanned HCU. Background Migraine is a common, disabling
Megan Trenz, Raja Narendra Divakar Addanki, Jason Raad, Robert Kaniecki, Janel Hanmer, Manisha Jhamb, Wesley T. Kerr, Parthasarathy D. Thirumala   +7 more
wiley   +1 more source

MaMi study: Perceptions of pregnancy and reproductive decision‐making in women with migraine

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To characterize the influence of migraine on reproductive decision‐making in women of childbearing age and to identify potentially modifiable beliefs that could guide preconception counseling in headache clinical practice. Background Migraine is a highly prevalent neurological disorder that disproportionately affects women of ...
Nuria González‐García, Blanca Hidalgo Valverde, Ana Beatriz Gago‐Veiga, Sonia Quintas, Alicia Gonzalez‐Martinez, Jaime Rodríguez Vico, Alex Jaimes, Andrea Gómez García, Germán Latorre González, Carlos A. Calle de Miguel, Javier Díaz de Terán Velasco, David García‐Azorín, Ángel Luis Guerrero Peral, María Luz Cuadrado, Jesús Porta‐Etessam   +14 more
wiley   +1 more source

RETRACTED: Mancinelli et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. Cells 2022, 11, 1591

Cells
The journal retracts the article titled “The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling” [...]
Romina Mancinelli, Ludovica Ceci, Lindsey Kennedy, Heather Francis, Vik Meadows, Lixian Chen, Guido Carpino, Konstantina Kyritsi, Nan Wu, Tianhao Zhou, Keisaku Sato, Luigi Pannarale, Shannon Glaser, Sanjukta Chakraborty, Gianfranco Alpini, Eugenio Gaudio, Paolo Onori, Antonio Franchitto   +17 more
doaj   +1 more source

Increase and regulation of synovial calcitonin gene-related peptide expression in patients with painful knee osteoarthritis

, 2017
Shotaro Takano*, Kentaro Uchida*, Gen Inoue, Atsushi Minatani, Masayuki Miyagi, Jun Aikawa, Dai Iwase, Kenji Onuma, Manabu Mukai, Masashi Takaso Department of Orthopedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan *These authors ...
Onuma K, Mukai M, Takano S, Miyagi M, Minatani A, Uchida K, Aikawa J, Iwase D, Takaso M, Inoue G   +9 more
core  

Development of a machine learning (ML) model to predict 3‐month response to CGRP monoclonal antibodies in migraine: A pilot evaluation of physician‐ML model interaction

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Monoclonal antibodies that target calcitonin gene‐related peptide (CGRP‐mAbs) are effective treatments for preventing migraine in many patients but are expensive, and physicians cannot easily predict which patients will benefit from them.
Masahito Katsuki, Muneto Tatsumoto, Tomokazu Shimazu, Yasuhiko Matsumori, Marina Romozzi, Omid Kohandel Gargari, Alicia Gonzalez‐Martinez, Woo‐Seok Ha, Yutaro Fuse, Shiho Suzuki, Saro Kobayashi, Tomohiko Shiina, Mukuto Shioda, Hiroaki Fujita, Koichi Hirata, Yuya Kano, Ryosuke Fukazawa, Jackson T. S. Cheung, Siobhán O'Connor, Tomás Ward, Kieran Moran, Keisuke Suzuki   +21 more
wiley   +1 more source

Variations in Calcitonin Gene-Related Peptide, Adiponectin, and Ghrelin Levels and Their Effects on Preeclampsia

Clinical and Experimental Obstetrics & Gynecology
Background: This study aimed to investigate serum levels of calcitonin gene-related peptide (CGRP) and explore potential associations between serum CGRP, adiponectin, and ghrelin concentrations in patients with preeclampsia.
Özlem Koşar Can, Umit Cabus, Cihan Kabukcu, Semin Fenkci, Veysel Fenkci, Yasar Enli   +5 more
doaj   +1 more source

The MIND study: Design, feasibility, and baseline characteristics of a smartphone‐based migraine cohort

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Our objective was to describe the design, feasibility, and baseline characteristics of the Migraine Impact on Neurocognitive Dynamics study, a 30‐day smartphone‐based, prospective, decentralized, observational cohort study evaluating high‐frequency assessment of cognition and symptoms in adults with migraine.
Babak Khorsand, Devin Teichrow, Richard B. Lipton, Ali Ezzati   +3 more
wiley   +1 more source

Longitudinal effects of CGRP‐targeting migraine therapies on blood pressure and body mass index: A 12‐month retrospective analysis

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To compare blood pressure (BP) and body mass index (BMI) trajectories associated with individual calcitonin gene‐related peptide (CGRP)‐targeting migraine therapies versus matched CGRP‐unexposed controls. Background CGRP is a potent vasodilator with established roles in vascular homeostasis and metabolic regulation.
Phillip Phan, Scott Keith, Michael Li, Richard Hass, Wan‐Jen Hsieh, Michael Marmura, Hsiangkuo Yuan   +6 more
wiley   +1 more source