Results 111 to 120 of about 11,435,493 (279)

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

[Calcitonin gene related peptide].

Postepy higieny i medycyny doswiadczalnej, 1996
Paper presents a recent review on the function and practical importance of CGRP in both physiology and pathology of animals and humans. The special attention was paid on CGRP role in cardiovascular, endocrine and gastrointestinal systems and in neoplasms.
Z, Zdrojewicz, M, Bolanowski, G, Drumlak, M, Zabel, A, Januszewski   +4 more
openaire   +1 more source

Real‐world outcomes of zavegepant use in a tertiary care setting using the Migraine Treatment Optimization Questionnaire‐5

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background The introduction of calcitonin gene‐related peptide antagonists has transformed migraine care. Zavegepant, a third‐generation intranasal gepant, offers a nonoral treatment option for acute migraine. Although clinical trials support its efficacy and safety, real‐world data are limited.
Eric Dunn, Bradley Ong, Harpreet Kaur, Roman Popov, Claire Sonneborn, Aarushi Suneja   +5 more
wiley   +1 more source

Variations in Calcitonin Gene-Related Peptide, Adiponectin, and Ghrelin Levels and Their Effects on Preeclampsia

Clinical and Experimental Obstetrics & Gynecology
Background: This study aimed to investigate serum levels of calcitonin gene-related peptide (CGRP) and explore potential associations between serum CGRP, adiponectin, and ghrelin concentrations in patients with preeclampsia.
Özlem Koşar Can, Umit Cabus, Cihan Kabukcu, Semin Fenkci, Veysel Fenkci, Yasar Enli   +5 more
doaj   +1 more source

Calcitonin gene related peptide relaxes cholecystokinin-induced contraction in guinea pig gallbladder strips in vitro

, 1992
Calcitonin gene related peptide has been shown to relax vascular and intestinal smooth muscle. This study examines the effects of calcitonin gene related peptide on cholecystokinin-induced contraction of guinea pig gallbladder strips in vitro ...
P. K. T. Pang, L. W. Kline
core   +1 more source

Responding With Evidence and Access for Childhood Headaches (REACH) study: A comparative effectiveness trial of cognitive behavioral therapy monotherapy versus combined cognitive behavioral therapy–pharmacotherapy with amitriptyline for the prevention of childhood migraine—The study protocol

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Migraine is one of the most common chronic health problems in children and adolescents, resulting in high levels of functional disability. Symptoms frequently persist into and impact the course of adulthood for affected individuals. Current practice recommendations include a combined therapy approach of preventive medication and cognitive ...
Estée C. H. Feldman, Michelle M. Ernst, Maya A. Marzouk, Robert C. Gibler, Brooke L. Reidy, Leigh A. Chamberlin, Megan Kirschman, James Peugh, Marielle Kabbouche, Susan L. LeCates, Joanne Kacperski, Jessica A. Saunders, Andrew D. Hershey, Marcy E. Yonker, Christina L. Szperka, Amy A. Gelfand, Scott W. Powers, on behalf of the REACH Study Investigators, Joanne Kacperski, Jennifer McVige, Frank Berenson, Chaouki Khoury, Judy Adelizzi‐Delany, Marcy Yonker, Elizabeth Ackley, J. Ivan Lopez, Ann Pakalnis, Sara Pavitt, Scott Turner, Elizabeth Doll, Michael Sowell, Rachel Evans, Lauren Evanczyk, Reena Rastogi, Amy Gelfand, Hannah Shapiro, Christina Szperka, Ankita Gosh, Rashmi Rao   +38 more
wiley   +1 more source

Personalized machine learning prediction of next‐day migraine persistence using digital headache diary data

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Migraine is a disabling neurological disorder with substantial interindividual variability. Predicting whether an ongoing migraine attack will persist into the following day remains challenging. We evaluated the feasibility and predictive performance of personalized machine learning models for predicting next‐day migraine
Ya‐Hsiu Tsai, Chen‐Lin Chiou, Jun‐Jun Lee, Chun‐Ming Yang, Kao‐Chang Lin, Tain‐Junn Cheng, Ja‐Hwung Su, Cheng‐Hsin Chuang   +7 more
wiley   +1 more source

Quantitative Structure-Activity Relationships and Docking Studies of Calcitonin Gene-Related Peptide Antagonists

, 2011
Defining the role of calcitonin gene-related peptide in migraine pathogenesis could lead to the application of calcitonin gene-related peptide antagonists as novel migraine therapeutics. In this work, quantitative structure-activity relationship modeling
Anahita Kyani, Jenssen, Håvard, Mohadeseh Mehrabian, Kyani, Anahita, Håvard Jenssen, Mehrabian, Mohadeseh   +5 more
core   +1 more source

Targeted liquid chromatography–tandem mass spectrometry profiling of arginine and histidine derivatives in chronic migraine: Discriminatory performance and changes after onabotulinumtoxinA therapy

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary People with chronic migraine may have changes in amino‐acid metabolism, but it remains unclear which metabolic pathways are associated with the disease and early response to onabotulinumtoxinA treatment. We measured plasma amino‐acid levels in patients with chronic migraine and healthy controls and assessed changes after 1 month ...
Seyma Dumur, Kadidiatou Diarra, Joudy Sewidan, Julie Jalila Kalmoni, Demet Aygun, Dildar Konukoglu, Hafize Uzun   +6 more
wiley   +1 more source

Real-World Clinical Effectiveness and Migraine-Related Healthcare Resource Utilization in Patients Initiating Fremanezumab in Germany and the United Kingdom

Therapeutics and Clinical Risk Management
Axel Heinze,1 Shazia K Afridi,2 Todor I Totev,3 Lynda J Krasenbaum,4 Emi Terasawa,5 Hasan Akcicek,6 Joachim Hipp,7 Dalbir Dhiraj,8 Rochelle Sun,3 Erica Yim,5 Binyam Yilma,5 Maurice T Driessen9 1Migraine and Headache Center, Pain Clinic Kiel, Kiel ...
Heinze A, Afridi SK, Totev TI, Krasenbaum LJ, Terasawa E, Akcicek H, Hipp J, Dhiraj D, Sun R, Yim E, Yilma B, Driessen MT   +11 more
doaj