Results 121 to 130 of about 11,435,493 (279)

Calcitonin Gene-Related Peptide Terminates Long-Lasting Vasopressor Responses to Endothelin 1 In Vivo

, 2011
Slow dissociation of endothelin 1 from its endothelin A receptors is responsible for the long-lasting vasoconstrictor effects of the peptide. We showed recently that calcitonin gene-related peptide selectively terminates long-lasting contractile ...
Meens, Merlijn J. P. M. T., De Mey, Jo G. R., Nelissen, Jelly, Jelly Nelissen, Nadine J.A. Mattheij, Pieter Lemkens, Matthijs G. Compeer, Merlijn J.P.M.T. Meens, Mattheij, Nadine J. A., Jo G.R. De Mey, Lemkens, Pieter, Janssen, Ben J. A., Ben J.A. Janssen, Compeer, Matthijs G.   +13 more
core   +1 more source

Early improvements in function with atogepant as assessed by the Activity Impairment in Migraine–Diary: Post hoc analyses of three randomized, phase 3 clinical trials of atogepant for the preventive treatment of migraine

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective Evaluate early functional improvements with the preventive migraine treatment atogepant using Activity Impairment in Migraine–Diary (AIM‐D) individual and activity limitation items, and complete improvement in AIM‐D Performance of Daily Activities (PDA) and Physical Impairment (PI) domain scores assessed weekly during the first 4 ...
Richard B. Lipton, Pranav Gandhi, Andreas R. Gantenbein, Brett Dabruzzo, Karen Carr, Jonathan Stokes, Molly Duan, Rashmi B. Halker Singh, Hsiangkuo Yuan, Dawn C. Buse   +9 more
wiley   +1 more source

Calcitonin gene-related peptide induced migraine attacks in patients with and without familial aggregation of migraine

, 2017
Background Calcitonin gene-related peptide provokes migraine attacks in 65% of patients with migraine without aura. Whether aggregation of migraine in first-degree relatives (family load) or a high number of risk-conferring single nucleotide ...
Christensen, Anne Francke, Janjooa, Benjamin Naveed, Ashina, Messoud, Olesen, Jes, Guo, Song, Liu, Marie Louise   +5 more
core   +1 more source

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson, D. Edwards, Q. Vuong, I. Obara   +3 more
wiley   +1 more source

Expression of calcitonin gene-related peptide and pulp sensitivity tests in irreversible pulpitis

Brazilian Oral Research
The aim of the present study was to identify the relationship between the expression of calcitonin gene-related peptide (CGRP) and the responses of pulp sensitivity tests in healthy pulps and irreversible pulps by performing a cross-sectional study on ...
Brenda Eréndida CASTILLO-SILVA, Verónica MARTÍNEZ-JIMÉNEZ, Gabriel Alejandro MARTÍNEZ- CASTAÑÓN, Carlo Eduardo MEDINA-SOLÍS, Eva Concepción AGUIRRE-LÓPEZ, Jesús Ramón CASTILLO-HERNÁNDEZ, Nereyda NIÑO-MARTÍNEZ, Nuria PATIÑO-MARÍN   +7 more
doaj   +1 more source

Calcitonin and calcitonin gene-related peptide interact with the same receptor in cultured LLC-PK1 kidney cells

, 1985
Calcitonin and calcitonin gene-related peptide stimulate adenylate cyclase activity and plasminogen activator production in cultured renal tubular LLC-PK1 cells.
Fischer, J. A., Vassalli, Jean-Dominique, Wohlwend, Annelise Isabelle, Malmstrom, K., Henke, H., Murer, H.   +5 more
core  

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Followup Results of a Combination of Calcitonin Gene-Related Peptide and Prostaglandin E1 in the Treatment of erectile Dysfunction. [PDF]

, 1993
Kuczyk, M., Stief, Christian Georg, Mohamad Djamilian, Markus Kuczyk, Jonas, Udo, Christian G. Stief, Djamilian, Mohamad H., Udo Jonas   +7 more
core   +1 more source

Multiscale analysis of the adult human superior hypogastric plexus and hypogastric nerve

Journal of Anatomy, EarlyView.
Using tissue clearing and light‐sheet microscopy methods, we visualized the 3D mesoscopic arrangement of neural tracts, blood vessels and neurons within the adult human superior hypogastric plexus and hypogastric nerves, identifying the latter to contain thousands of neuronal cells bodies embedded along its entire length.
Kayleigh S. Scotcher, John‐Paul Fuller‐Jackson, Peregrine B. Osborne, Martin M. Bertrand, Janet R. Keast   +4 more
wiley   +1 more source

Safety and tolerability of atogepant for the preventive treatment of migraine: a post hoc analysis of pooled data from four clinical trials

The Journal of Headache and Pain
Background Conventional, non-specific preventive migraine treatments often demonstrate low rates of treatment persistence due to poor efficacy or tolerability.
Paul Rizzoli, Michael J. Marmura, Jennifer Robblee, Jennifer McVige, Sara Sacco, Stephanie J. Nahas, Jessica Ailani, Rosa De Abreu Ferreira, Julia Ma, Jonathan H. Smith, Brett Dabruzzo, Messoud Ashina   +11 more
doaj   +1 more source