Results 141 to 150 of about 11,435,493 (279)

Women with a history of gestational diabetes mellitus have preserved sensory nerve‐mediated dilatation in the cutaneous microvasculature

open access: yesExperimental Physiology, EarlyView.
Abstract Women with a history of gestational diabetes mellitus (GDM) have a greater risk of developing type 2 diabetes mellitus and cardiovascular disease than healthy control (HC) women who had an uncomplicated pregnancy. Microvascular endothelial dysfunction, mediated by reduced nitric oxide (NO)‐dependent mechanisms, persists after GDM.
Grace S. Maurer   +3 more
wiley   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Calcitonin receptor, calcitonin gene-related peptide and amylin distribution in C1/2 dorsal root ganglia

open access: yesThe Journal of Headache and Pain
Background The upper cervical dorsal root ganglia (DRG) are important for the transmission of sensory information associated with the back of the head and neck, contributing to head pain.
Tayla A. Rees   +5 more
doaj   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla   +3 more
wiley   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Calcitonin gene-related peptide and traumatic brain injury

open access: yesNeural Regeneration Research, 2019
Saul Almeida da Silva   +3 more
doaj   +1 more source

Peripheral regeneration of Aβ low‐threshold mechanoreceptors is limited despite activation of regenerative transcriptional pathways

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The regeneration of Aβ low‐threshold mechanoreceptors (Aβ‐LTMRs), sensory neurons responsible for discriminative touch, has not previously been explored. Here, we took advantage of the selective expression of Calb1 in Aβ‐LTMRs to generate two genetic mouse models for studying their regenerative response after nerve injury.
Sara Bolívar   +3 more
wiley   +1 more source

The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley   +1 more source

Axial Connectivity of the Lung Microbiome: A Review of Interorgan Crosstalk

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
The human microbiome mediates immune homeostasis and metabolic signaling across organs. Beyond the gut‐lung axis, crosstalk between the lung and other organ systems is less recognized. This review assesses the axial connectivity of the lung microbiome across the gut, brain, skin, heart, kidney, and liver.
Mathangi Palanivel   +2 more
wiley   +1 more source

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