Results 141 to 150 of about 13,600,961 (272)
Understanding exosomes in diabetic wound healing
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
Calcitonin gene-related peptide and traumatic brain injury
Saul Almeida da Silva +3 more
doaj +1 more source
Abstract Women with a history of gestational diabetes mellitus (GDM) have a greater risk of developing type 2 diabetes mellitus and cardiovascular disease than healthy control (HC) women who had an uncomplicated pregnancy. Microvascular endothelial dysfunction, mediated by reduced nitric oxide (NO)‐dependent mechanisms, persists after GDM.
Grace S. Maurer +3 more
wiley +1 more source
Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
High‐altitude headache: Insights into pathophysiology and potential treatment implications
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla +3 more
wiley +1 more source
Calcitonin Gene-Related Peptide in Tension-Type Headache
Messoud Ashina
doaj +1 more source
Hypoxia‐induced vulnerability of the somatosensory nervous system
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley +1 more source
Could calcitonin gene-related peptide inhibitors prevent status epilepticus? [PDF]
Nsaka M +6 more
europepmc +1 more source
Abstract figure legend The regeneration of Aβ low‐threshold mechanoreceptors (Aβ‐LTMRs), sensory neurons responsible for discriminative touch, has not previously been explored. Here, we took advantage of the selective expression of Calb1 in Aβ‐LTMRs to generate two genetic mouse models for studying their regenerative response after nerve injury.
Sara Bolívar +3 more
wiley +1 more source
Current Evidence on the Use of Calcitonin Gene-Related Peptide-Targeting Therapies in Children and Adolescents. [PDF]
Shin L, Moon R, Gelfand A.
europepmc +1 more source

