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Ontogeny of calcitonin gene-related peptide and calcitonin in the rat thyroid
Histochemistry, 1986In this immunohistochemical study, the ontogenic development of calcitonin-gene-related peptide (CGRP) in the rat thyroid was investigated and compared with that of calcitonin using the indirect-immunofluorescence method. Parafollicular cells with immunoreactivity to both CGRP and calcitonin first appeared at an early stage of gestation (days 17 and 18)
K, Nitta +6 more
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CALCITONIN GENE‐RELATED PEPTIDE AND CALCITONIN IN MEDULLARY THYROID CARCINOMA
Clinical Endocrinology, 1986SUMMARYWe have investigated the levels of serum calcitonin and calcitonin‐gene related peptide (CGRP) in 35 patients with well‐documented medullary thyroid carcinoma (MTC). Immunohistochemical investigations for calcitonin and CGRP have been performed on tumour tissue from 9 patients to clarify the cellular pattern of production.
S, Schifter +3 more
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Serotonin, calcitonin and calcitonin gene-related peptide in acute pancreatitis
Scandinavian Journal of Gastroenterology, 2017The aim of this study was to investigate plasma levels of serotonin, calcitonin and calcitonin gene-related peptide (CGRP) in the course of acute pancreatitis (AP) taking organ failure, etiology and severity into consideration.Sixty consecutive patients with alcohol- or gallstone-induced AP were included over a 15-month period.
Kirsten Lykke Wahlstrøm +5 more
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Calcitonin Gene Related Peptide
1994A 37 amino acid peptide which is an alternative product of the calcitonin/CGRP genes, and is expressed in the thyroid and central and peripheral nervous tissue.
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Calcitonin gene-related peptide as inflammatory mediator
Pulmonary Pharmacology & Therapeutics, 2003Sensory neuropeptides have been proposed to play a key role in the pathogenesis of a number of respiratory diseases such as asthma, chronic obstructive pulmonary disease or chronic cough. Next to prominent neuropeptides such as tachykinins or vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP) has long been suggested to ...
J. Springer +3 more
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Calcitonin gene‐related peptide and reperfusion injury
Journal of Orthopaedic Research, 1997AbstractCalcitonin gene‐related peptide is a potent intrinsic vasodilator, can induce prostacyclin release, and may inhibit membrane lipid peroxidation. This study examines the effect of calcitonin gene‐related peptide on vessel diameters, capillary perfusion and contractile function of skeletal muscle after 4 or 5 hours of ischemia and during ...
D M, Allen +3 more
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Constrained Analogues of the Calcitonin Gene-Related Peptide
Biochemical and Biophysical Research Communications, 1994The calcitonin gene-related peptide, CGRP, has potential medicinal use for instance as a vasodilator or in the regulation of bone metabolism. In this study new analogues of CGRP based on molecular modelling of active fragments were synthesised and tested.
J M, Hakala +6 more
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CALCITONIN GENE RELATED PEPTIDE
Inpharma Weekly, 1992ALIVERTI VALERIO +3 more
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