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Calcitonin Gene-Related Peptide (CGRP)-Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain-Induced Sleep Disturbances. [PDF]
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Erratum in: Calcitonin Gene-Related Peptide Regulates Specific Interferon-Stimulating Genes to Inhibit Apoptosis of Corneal Epithelial Cells in Dry Eye Disease. [PDF]
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Calcitonin and Calcitonin Gene-Related Peptide
1989The Ca++ ion plays a critical role in neuronal transmission. Therefore, agents capable of modulating it can exert profound effects on the cell’s ability to interpret extracellular signals. In 1964, Hano et al.1 reported that intracisternal Ca++ administration antagonized the action of morphine, which, conversely, was potentiated by the Ca++ chelator ...
Sandra P. Welch, William L. Dewey
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Calcitonin gene-related peptide and hypertension
Peptides, 2005Capsaicin-sensitive sensory nerves participate in the regulation of cardiovascular functions both in the normal state and the pathophysiology of hypertension through the actions of potent vasodilator neuropeptides, including calcitonin gene-related peptide (CGRP).
Pan-Yue, Deng, Yuan-Jian, Li
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Calcitonin gene-related peptide and migraine
Current Opinion in Neurology, 2015Migraine is a common, complex disorder of the brain with significant morbidity. As the pathophysiology of the disorder has become better appreciated, the role of neuropeptides has been explored. Calcitonin gene-related peptide (CGRP) has emerged as a promising therapeutic target.CGRP is widely distributed in the nervous system, particularly at ...
Karsan, Nazia, Goadsby, Peter J.
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Calcitonin gene-related peptide: Novel neuropeptide
Life Sciences, 1986Calcitonin gene-related peptide (CGRP) is a 37 amino acid peptide encoded in the calcitonin gene. Its expression is dependent on tissue-specific alternative RNA processing: mRNA for CGRP predominates in the brain, whilst calcitonin (CT) mRNA predominates in thyroid C cells.
E C, Goodman, L L, Iversen
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Molecular and Cellular Endocrinology, 2003
In this study, we describe the cloning and tissue expression of equine calcitonin (CT), calcitonin-gene related peptide (CGRP)-I, and CGRP-II cDNA. We also describe a novel divergent form of CGRP (CGRP-I). Equine CT has greatest homology (>85%) to human, rat and mouse subgroups of calcitonins.
Ramiro E, Toribio +4 more
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In this study, we describe the cloning and tissue expression of equine calcitonin (CT), calcitonin-gene related peptide (CGRP)-I, and CGRP-II cDNA. We also describe a novel divergent form of CGRP (CGRP-I). Equine CT has greatest homology (>85%) to human, rat and mouse subgroups of calcitonins.
Ramiro E, Toribio +4 more
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Calcitonin Gene Related Peptide
1994A 37 amino acid peptide which is an alternative product of the calcitonin/CGRP genes, and is expressed in the thyroid and central and peripheral nervous tissue.
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