Results 31 to 40 of about 13,600,961 (272)

Calcitonin gene-related peptide is potential therapeutic target of osteoporosis

Heliyon, 2022
Osteoporosis is a skeletal disorder characterised by the decrease of bone mineral density and is becoming prevalent with the entry of an ageing era.
Hua Wu, Xue-qin Lin, Yu Long, Jing Wang
doaj   +1 more source

Voluntary Forelimbs Exercise Reduces Immobilization-Induced Mechanical Hyperalgesia in the Rat Hind Paw

Pain Research and Management, 2021
Voluntary exercise is sufficient to protect against neuropathic pain. However, it is unclear whether voluntary exercise reduces immobilization-induced hyperalgesia. We examined the effect of voluntary forelimb exercise on immobilized-induced hyperalgesia
Kumiko Ishikawa, Satoshi Oga, Kyo Goto, Junya Sakamoto, Ryo Sasaki, Yuichiro Honda, Hideki Kataoka, Minoru Okita   +7 more
doaj   +1 more source

Circulating Levels of Calcitonin Gene-Related Peptide in Patients with Medullary Thyroid Carcinoma [PDF]

, 1988
Summary: Calcitonin gene-related peptide, originally found in rat medullary thyroid carcinoma cells, was measured by radioimmunpassay in plasma samples with added aprotinin from 17 normal volunteers and 21 patients with medullary thyroid carcinoma.
Kawai, Yuriko, Toshio Onishi, Shigeto Morimoto, Onishi, Toshio, Shouei Kim, Morimoto, Shigeto, Yuriko Kawai, Eio Koh, Ogihara, Toshio, Toshio Ogihara, Kim, Shouei, Koh, Eio   +11 more
core   +1 more source

Effects of Calcitonin-Gene-Related-Peptide on Auditory Nerve Activity

Frontiers in Cell and Developmental Biology, 2021
Calcitonin-gene-related peptide (CGRP) is a lateral olivocochlear (LOC) efferent neurotransmitter. Depression of sound-driven auditory brainstem response amplitude in CGRP-null mice suggests the potential for endogenous CGRP release to upregulate ...
Colleen G. Le Prell, Colleen G. Le Prell, Larry F. Hughes, David F. Dolan, Sanford C. Bledsoe   +4 more
doaj   +1 more source

Treating Menière’s disease with rimegepant

Swiss Medical Weekly
A recent hypothesis states that Menière’s disease is caused by inappropriate expression, i.e. enhanced release of the neurotransmitter calcitonin gene-related peptide.
Stefan C. A. Hegemann, Angela Schell
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Clinical Review of Calcitonin Gene-Related Peptide Inhibitors for Migraines

, 2023
Migraine is a complex, ubiquitous debilitating neurovascular disorder affecting over one billion people, transcending adult and pediatric populations, gender, and ethnicity.
Martin, Sandrine N.
core   +1 more source

Role of Calcitonin Gene-Related Peptide in Inhibitory Neurotransmission to the Pig Bladder Neck

, 2011
Purpose: We studied the role of calcitonin gene-related peptide in nonadrenergic, noncholinergic neurotransmission to the pig bladder neck. Materials and Methods: We used immunohistochemical techniques to determine the distribution of calcitonin gene ...
Joaquín Carballido, García-Sacristán, Albino, Hernández Rodríguez, Medardo Vicente, Medardo Hernández, Paz Recio, Ana Martínez-Sáenz, Orensanz, Luis M., Carballido, Joaquín, María Pilar Martínez, Bustamante, Salvador, Luis M. Orensanz, Martínez Sainz, María Del Pilar, Vítor S. Fernandes, Salvador Bustamante, Dolores Prieto, Leite Fernandes, Vitor Samuel, Albino García-Sacristán, Martínez-Sáenz, Ana, Recio Visedo, María Paz, Prieto Ocejo, Dolores   +19 more
core   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease [PDF]

, 2008
Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Jian Zhuang, Hongsui Wu, Shiliang Chen, Jian Su, Yuhui Zheng, Xiaoning Zhang, Jianguang Chen, Huanxin Yang, Zhihong Chen   +8 more
core