Results 11 to 20 of about 13,600,961 (272)

Calcitonin Gene-Related Peptide (CGRP) in Cerebrovascular Disease

The Scientific World Journal, 2002
Cerebral blood vessels are innervated by sensory nerves that store several neurotransmitters among which calcitonin gene-related peptide (CGRP) is the most abundant. In primary headaches, there is a clear association between the head pain and the release
Lars Edvinsson
doaj   +2 more sources

Receptors for calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin

Canadian Journal of Physiology and Pharmacology, 1995
Calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin are structurally related polypeptides characterized by a six or seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus. They exhibit overlapping biological actions as a result of cross-reactivity between the different receptors. In this article, the
Muff R, Born W, Fischer JA
openaire   +4 more sources

Overview of Calcitonin Gene-Related Peptide and Its Receptor [PDF]

The Scientific World Journal, 2001
Calcitonin Gene-Related Peptide (CGRP), a 37 amino acid peptide identified as the alternately spliced gene product of calcitonin gene, is a sensory neuropeptide with potent cardiovascular effects. CGRP is distributed throughout the central and peripheral
Nambi Aiyar
doaj   +3 more sources

Calcitonin gene-related peptide [PDF]

, 1993
Stief, Christian Georg, Bénard, Francois, Bosch, Ruud J. L. H., Wetterauer, Ulrich, Lue, Tom F., Tanagho, Emil A.   +5 more
openaire   +3 more sources

Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin [PDF]

Biochemical Journal, 1991
Near-u.v. and far-u.v. c.d. spectra of human alpha-calcitonin-gene-related peptide (h alpha CGRP), analogues and fragments of CGRP and amylin were recorded in aqueous solution and in trifluoroethanol (TFE)/water mixtures. All peptides contained significant amounts of alpha-helix in aqueous solution, and this amount increased on adding TFE.
J A, Hubbard, S R, Martin, L C, Chaplin, C, Bose, S M, Kelly, N C, Price   +5 more
openaire   +2 more sources

Calcitonin gene-related peptide is a stimulator of renin secretion [PDF]

, 1988
Calcitonin gene-related peptide (CGRP) was found to stimulate renin secretion in vivo in normal human volunteers. Moreover, CGRP stimulated the release of renin in vitro from isolated rat renal juxtaglomerular cells (half-maximal effective concentration [
Fischer, J. A., R Muff, Gnädinger, M. P., Uehlinger, D. E., Weidmann, P., A Kurtz, M P Gnädinger, W Born, Muff, R., J M Lundberg, T Hökfelt, P Weidmann, Kurtz, Armin, Lundberg, J. M., D E Uehlinger, Born, W., Millberg, B. I., Hökfelt, T., J A Fischer, B I Millberg, Weidmann P, Fischer JA, Millberg BI, Born W, Hökfelt T, Kurtz A, Uehlinger DE, Gnädinger MP, Lundberg JM, Muff R   +29 more
core   +1 more source

Calcitonin gene products and the kidney [PDF]

, 1989
Calcitonin gene-related peptide (CGRP) is localized in capsaicin-sensitive nerve fibres in the kidney and urogenital tract whereas calcitonin reaches the kidney through the general circulation.
Fischer, J. A., Kurtz, Armin, Muff, R., Fischer JA, Kurtz A, Muff R   +5 more
core   +1 more source

Renal mesangium is a target for calcitonin gene-related peptide [PDF]

, 1989
Rat calcitonin gene-related peptide (CGRP alpha; EC50, 1 nM) was shown to stimulate cAMP formation in cultured rat renal mesangial cells. CGRP concentration dependently (EC50, 1 nM) also inhibited contraction of mesangial cells by angiotensin II (10 nM).
Schurek, H. J., Heckmann, U., Scholz, Holger, Fischer, J. A., Bauer, Christian, Jelkmann, W., Muff, R., Kurtz, Armin, Lipp, H. P., Eckardt, Kai-Uwe, Roman Muff, Schurek HJ, Kai-Uwe Eckardt, Eckardt KU, Fischer JA, Bauer C, Armin Kurtz, Holger Scholz, Lipp HP, Heckmann U, Jan A. Fischer, Kurtz A, Jelkmann W, Christian Bauer, Hans-Joachim Schurek, Hans-Peter Lipp, Wolfgang Jelkmann, Uwe Heckmann, Scholz H, Muff R   +29 more
core   +1 more source

Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes [PDF]

, 2011
Context: Increased plasma levels of glucose-dependent insulinotropic polypeptide (GIP), calcitonin CT gene-related peptide (CGRP)-I, and procalcitonin (Pro-CT) are associated with obesity.
Beat Müller, Tanja Radimerski, Ralph Peterli, Ulrich Keller, Christ-Crain, Mirjam, Daniel M. Frey, Timper, Katharina, Frey, Daniel M., Mirjam Christ-Crain, Jean Grisouard, Häring, Andreas, Zulewski, Henryk, Keller, Ulrich, Grisouard, Jean, Katharina Timper, Henryk Zulewski, Radimerski, Tanja, Müller, Beat, Kaethi Dembinski, Dembinski, Kaethi, Andreas Häring, Peterli, Ralph, Christ-Crain M, Peterli R, Häring A, Frey DM, Müller B, Grisouard J, Keller U, Radimerski T, Zulewski H, Dembinski K, Timper K   +32 more
core   +1 more source

Phospholipase C gamma mediates endogenous brain-derived neurotrophic factor-regulated calcitonin gene-related peptide expression in colitis-induced visceral pain

Molecular Pain, 2016
Background Visceral hypersensitivity is a complex pathophysiological paradigm with unclear mechanisms. Primary afferent neuronal plasticity marked by alterations in neuroactive compounds such as calcitonin gene-related peptide is suggested to underlie ...
Fiza Hashmi MS, Miao Liu PhD, Shanwei Shen MS, Li-Ya Qiao PhD   +3 more
doaj   +1 more source