Results 11 to 20 of about 11,435,493 (279)

Calcitonin gene-related peptide [PDF]

Drugs & Aging, 1993
Stief, Christian Georg, Bénard, Francois, Bosch, Ruud J. L. H., Wetterauer, Ulrich, Lue, Tom F., Tanagho, Emil A.   +5 more
core   +5 more sources

The Role of Calcitonin Gene-Related Peptide in High-Altitude Headache: A Prospective Field Study. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Schniepp R, Karrasch L, Breitenstein H, Straube A, Kamm K.   +4 more
europepmc   +2 more sources

Calcitonin gene-related peptide is a stimulator of renin secretion [PDF]

, 1988
Calcitonin gene-related peptide (CGRP) was found to stimulate renin secretion in vivo in normal human volunteers. Moreover, CGRP stimulated the release of renin in vitro from isolated rat renal juxtaglomerular cells (half-maximal effective concentration [
Fischer, J. A., R Muff, Gnädinger, M. P., Uehlinger, D. E., Weidmann, P., A Kurtz, M P Gnädinger, W Born, Muff, R., J M Lundberg, T Hökfelt, P Weidmann, Kurtz, Armin, Lundberg, J. M., D E Uehlinger, Born, W., Millberg, B. I., Hökfelt, T., J A Fischer, B I Millberg   +19 more
core   +1 more source

Calcitonin gene products and the kidney [PDF]

, 1989
Calcitonin gene-related peptide (CGRP) is localized in capsaicin-sensitive nerve fibres in the kidney and urogenital tract whereas calcitonin reaches the kidney through the general circulation.
Fischer, J. A., Kurtz, Armin, Muff, R.
core   +1 more source

Renal mesangium is a target for calcitonin gene-related peptide [PDF]

, 1989
Rat calcitonin gene-related peptide (CGRP alpha; EC50, 1 nM) was shown to stimulate cAMP formation in cultured rat renal mesangial cells. CGRP concentration dependently (EC50, 1 nM) also inhibited contraction of mesangial cells by angiotensin II (10 nM).
Schurek, H. J., Heckmann, U., Scholz, Holger, Fischer, Jan A., Fischer, J. A., Bauer, Christian, Lipp, Hans-Peter, Jelkmann, W., Muff, R., Heckmann, Uwe, Kurtz, Armin, Lipp, H. P., Schurek, Hans-Joachim, Jelkmann, Wolfgang, Muff, Roman, Eckardt, Kai-Uwe   +15 more
core   +1 more source

Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes [PDF]

, 2011
Context: Increased plasma levels of glucose-dependent insulinotropic polypeptide (GIP), calcitonin CT gene-related peptide (CGRP)-I, and procalcitonin (Pro-CT) are associated with obesity.
Beat Müller, Tanja Radimerski, Ralph Peterli, Ulrich Keller, Christ-Crain, Mirjam, Daniel M. Frey, Timper, Katharina, Frey, Daniel M., Mirjam Christ-Crain, Jean Grisouard, Häring, Andreas, Zulewski, Henryk, Keller, Ulrich, Grisouard, Jean, Katharina Timper, Henryk Zulewski, Radimerski, Tanja, Müller, Beat, Kaethi Dembinski, Dembinski, Kaethi, Andreas Häring, Peterli, Ralph   +21 more
core   +1 more source

Distinct calcitonin gene-related peptide expression pattern in primary afferents contribute to different neuropathic symptoms following chronic constriction or crush injuries to the rat sciatic nerve

Molecular Pain, 2016
Although calcitonin gene-related peptide is a recognized pain transducer, the expression of calcitonin gene-related peptide in primary afferents may be differentially affected following different types of nerve injury. Here, we examined whether different
Yu Zou PhD, Fangting Xu PhD, Zhaohui Tang MD, Tao Zhong PhD, Jiawei Cao MD, Qulian Guo PhD, Changsheng Huang MD   +6 more
doaj   +1 more source

Phospholipase C gamma mediates endogenous brain-derived neurotrophic factor-regulated calcitonin gene-related peptide expression in colitis-induced visceral pain

Molecular Pain, 2016
Background Visceral hypersensitivity is a complex pathophysiological paradigm with unclear mechanisms. Primary afferent neuronal plasticity marked by alterations in neuroactive compounds such as calcitonin gene-related peptide is suggested to underlie ...
Fiza Hashmi MS, Miao Liu PhD, Shanwei Shen MS, Li-Ya Qiao PhD   +3 more
doaj   +1 more source

Exploring Ligand Binding to Calcitonin Gene-Related Peptide Receptors

Frontiers in Molecular Biosciences, 2021
Class B1 G protein-coupled receptors (GPCRs) are important targets for many diseases, including cancer, diabetes, and heart disease. All the approved drugs for this receptor family are peptides that mimic the endogenous activating hormones.
Giuseppe Deganutti, Silvia Atanasio, Roxana-Maria Rujan, Patrick M. Sexton, Patrick M. Sexton, Denise Wootten, Denise Wootten, Christopher A. Reynolds   +7 more
doaj   +1 more source

Calcitonin receptor-like receptor is expressed on gastrointestinal immune cells [PDF]

, 2002
Background/Aims: Pharmacological and morphological studies suggest that the gut mucosal immune system and local neuropeptide-containing neurones interact.
Göke, B., Haberberger, R., Knauer, J., McGregor, G. P., Hagner, S., Voigt, K.   +5 more
core   +1 more source