Results 1 to 10 of about 3,644,890 (211)
The calcium–cancer signalling nexus
Nature Reviews Cancer, 2017 Gregory R Monteith
exaly +2 more sources
Cell Death Discovery, 2021 A Correction to this paper has been published: https://doi.org/10.1038/s41420-021-00445 ...
Farai C. Gombedza +3 more
doaj +1 more source
Development and characterization of a monoclonal antibody blocking human TRPM4 channel
Scientific Reports, 2021 TRPM4 is a calcium-activated non-selective monovalent cation channel implicated in diseases such as stroke. Lack of potent and selective inhibitors remains a major challenge for studying TRPM4.
See Wee Low +5 more
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Scientific Reports, 2021 Excessive salt intake has been associated with the development of non-communicable diseases, including hypertension with several cardiovascular consequences.
Wacharaporn Tiyasatkulkovit +9 more
doaj +1 more source
Fast and sensitive GCaMP calcium indicators for imaging neural populations
bioRxiv, 2021 Using large-scale screening and structure-guided mutagenesis, fast and sensitive GCaMP sensors are developed and optimized with improved kinetics without compromising sensitivity or brightness.
Yan Zhang +23 more
semanticscholar +1 more source
Scientific Reports, 2023 Iron overload negatively affects bone mass and strength. However, the impact of iron excess on osteocytes—important bone cells for mechanotransduction and remodeling—is poorly understood.
Wasutorn Chankamngoen +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 In stroke and other neurological diseases, Transient Receptor Potential Melastatin 4 (TRPM4) has been reported to cause oncotic cell death which is due to an excessive influx of sodium ions.
Shunhui Wei +8 more
doaj +1 more source
Ablation of TRPC3 disrupts Ca2+ signaling in salivary ductal cells and promotes sialolithiasis
Scientific Reports, 2023 Clinical studies and structural analyses of salivary stones strongly suggest a linkage between higher saliva calcium (Ca2+) and salivary stone formation, sialolithiasis; however, the process and the mechanism leading to Ca2+ overload during ...
Bok-Eum Choi +4 more
doaj +1 more source
TRPM4 Blocking Antibody Protects Cerebral Vasculature in Delayed Stroke Reperfusion
Biomedicines, 2023 Reperfusion therapy for acute ischemic stroke aims to restore the blood flow of occluded blood vessels. However, successful recanalization is often associated with disruption of the blood-brain barrier, leading to reperfusion injury.
Bo Chen +6 more
doaj +1 more source