Results 21 to 30 of about 3,765,678 (388)

Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia

open access: yesFrontiers in Cell and Developmental Biology, 2020
In stroke and other neurological diseases, Transient Receptor Potential Melastatin 4 (TRPM4) has been reported to cause oncotic cell death which is due to an excessive influx of sodium ions.
Shunhui Wei   +8 more
doaj   +1 more source

The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know

open access: yesJournal of Clinical Endocrinology and Metabolism, 2010
This article summarizes the new 2011 report on dietary requirements for calcium and vitamin D from the Institute of Medicine (IOM). An IOM Committee charged with determining the population needs for these nutrients in North America conducted a ...
A. Ross   +14 more
semanticscholar   +1 more source

HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis

open access: yesStem Cell Research & Therapy, 2023
Background Recent evidence suggests that accumulation of marrow adipose tissue induced by aberrant lineage allocation of bone marrow-derived mesenchymal stromal cells (BMSCs) contributes to the pathophysiologic processes of osteoporosis.
Shuang Zhang   +4 more
doaj   +1 more source

Relative Bioavailability of Calcium from Calcium Formate, Calcium Citrate, and Calcium Carbonate [PDF]

open access: yesThe Journal of Pharmacology and Experimental Therapeutics, 2005
Calcium is an essential nutrient required in substantial amounts, but many diets are deficient in calcium making supplementation necessary or desirable. The objective of this study was to compare the oral bioavailability of calcium from calcium formate, a new experimental dietary calcium supplement, to that of calcium citrate and calcium carbonate.
Hanzlik, Robert P.   +2 more
openaire   +3 more sources

Water calcium concentration modifies whole-body calcium uptake in sea bream larvae during short-term adaptation to altered salinities [PDF]

open access: yes, 2014
Whole-body calcium uptake was studied in gilthead sea bream larvae (9–83·mg) in response to changing environmental salinity and [Ca2+]. Calcium uptake increased with increased fish size and salinity.
Canario, Adelino V. M.   +5 more
core   +1 more source

Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration

open access: yesScientific Reports, 2022
The endocannabinoid system has been postulated to help restrict cancer progression and maintain osteoblastic function during bone metastasis. Herein, the effects of cannabinoid receptor (CB) type 1 and 2 activation on breast cancer cell and osteoblast ...
Tueanjai Khunluck   +7 more
doaj   +1 more source

The Effect of Treatment of Acidosis on Calcium Balance in Patients with Chronic Azotemic Renal Disease [PDF]

open access: yes, 1967
Small but statistically significant negative calcium balances were found in each of eight studies in seven patients with chronic azotemic renal disease when stable metabolic acidosis was present.
Lemann, Jacob, Jr.   +2 more
core   +3 more sources

Binding epitope for recognition of human TRPM4 channel by monoclonal antibody M4M

open access: yesScientific Reports, 2022
Mouse monoclonal antibody M4M was recently designed to block human TRPM4 channel. The polypeptide for generating M4M is composed of peptide A1 between the transmembrane segment 5 (S5) and the pore, and a second peptide A2 between the pore and the ...
Shunhui Wei   +6 more
doaj   +1 more source

Secretion of the Phosphorylated Form of S100A9 from Neutrophils Is Essential for the Proinflammatory Functions of Extracellular S100A8/A9

open access: yesFrontiers in Immunology, 2018
S100A8 and S100A9 are members of the S100 family of cytoplasmic EF-hand Ca2+-binding proteins and are abundantly expressed in the cytosol of neutrophils. In addition to their intracellular roles, S100A8/A9 can be secreted in the extracellular environment
Véronique Schenten   +7 more
doaj   +1 more source

Preparation and characterization of new hybrid organic/inorganic systems derived from calcium (aminoalkyl)-phosphonates and -phosphonocarboxylates [PDF]

open access: yes, 2005
We have studied the phenomenon of calcium complexation by lab synthesized amphiphilic (α-aminoalkyl)-phosphonocarboxylic or -phosphonic acids. The electrical conductivity of aqueous solutions of sodium salts of all these acids was measured versus the ...
Al-Ali, Fatima   +3 more
core   +2 more sources

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