Results 31 to 40 of about 3,765,678 (388)

Active regulation of the epidermal calcium profile [PDF]

open access: yes, 2012
A distinct calcium profile is strongly implicated in regulating the multi-layered structure of the epidermis. However, the mechanisms that govern the regulation of this calcium profile are currently unclear.
Adams, Matthew   +2 more
core   +2 more sources

Calcium signaling [PDF]

open access: yesCell, 1995
Calcium ions (Ca(2+)) impact nearly every aspect of cellular life. This review examines the principles of Ca(2+) signaling, from changes in protein conformations driven by Ca(2+) to the mechanisms that control Ca(2+) levels in the cytoplasm and organelles.
openaire   +3 more sources

When, where and how? Focus on neuronal calcium dysfunctions in Alzheimer's Disease. [PDF]

open access: yes, 2016
Alzheimer\u2019s disease (AD), since its characterization as a precise form of dementia with its own pathological hallmarks, has captured scientists\u2019 attention because of its complexity.
AGOSTINI, MARIO, FASOLATO, CRISTINA
core   +1 more source

Melamine promotes calcium crystal formation in three-dimensional microfluidic device

open access: yesScientific Reports, 2019
Melamine, which induces proximal tubular (PT) cell damage has a greater nephrotoxic effect when combined with cyanuric and uric acids; however, it is unknown whether such effect can stimulate calcium phosphate (CaP)/calcium oxalate (CaOx) stone formation.
Farai Gombedza   +6 more
doaj   +1 more source

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

open access: yesNature Methods, 2009
Genetically encoded calcium indicators (GECIs) can be used to image activity in defined neuronal populations. However, current GECIs produce inferior signals compared to synthetic indicators and recording electrodes, precluding detection of low firing ...
L. Tian   +13 more
semanticscholar   +1 more source

Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]

open access: yes, 2010
Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Belbraouet   +14 more
core   +4 more sources

Structural Determinants in the Calcitonin Receptor-Like Receptor (Crlr) Important for Cgrp and Adrenomedullin (Am) Receptor Function of Crlr/Receptor-Activity-Modifying Protein (Ramp) 1 and Crlr/Ramp2 Heterodimers

open access: yesThe Scientific World Journal, 2001
Cell surface protein cross-linking, coimmmunoprecipitation, and confocal microscopy identified CRLR/RAMP1-, CRLR/RAMP2-, and calcitonin receptor isotype 2 (CTR2)/RAMP1 heterodimers as CGRP-, AM-, and CGRP/amylin receptors, linked to cAMP production ...
W. Born   +4 more
doaj   +1 more source

Identification of small molecules as novel anti-adipogenic compounds based on Connectivity Map

open access: yesFrontiers in Endocrinology, 2022
Several physiological and pathological conditions such as aging, obesity, diabetes, anorexia nervosa are associated with increased adipogenesis in the bone marrow.
Shuang Zhang   +5 more
doaj   +1 more source

Bioactive calcium phosphate materials and applications in bone regeneration

open access: yesBiomaterials Research, 2019
BackgroundBone regeneration involves various complex biological processes. Many experiments have been performed using biomaterials in vivo and in vitro to promote and understand bone regeneration.
Jiwoong Jeong   +4 more
semanticscholar   +1 more source

Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart [PDF]

open access: yes, 2015
With aging, there is a decline in cardiac function accompanying increasing risk of arrhythmias. These effects are likely to be mechanistically associated with age-associated changes in calcium regulation within cardiac myocytes.
Close, Graeme L.   +6 more
core   +2 more sources

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