Results 111 to 120 of about 3,623,918 (405)

Ketamine effect on intracellular and mitochondrial calcium mobilization [PDF]

, 2016
The suppressive effects of ketamine on intracellular calcium has been reported in a variety of cells although the mechanisms involved are not well understood.
Bustamante, Jaunita, Czerniczyniec, Analia, Lores Arnaiz, Silvia   +2 more
core  

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Calcium channel blockade and survival in recipients of successful renal transplant: an analysis of the FAVORIT trial results

International Journal of Nephrology and Renovascular Disease, 2017
Larry A Weinrauch,1–4 Jiankang Liu,1 Brian Claggett,1 Peter V Finn,1 Matthew R Weir,5 John A D’Elia2–4 1Cardiovascular Division, Brigham and Women’s Hospital, 2Kidney and Hypertension Section, Joslin Diabetes Center, 3Department ...
Weinrauch LA, Liu J, Claggett B, Finn PV, Weir MR, D'Elia JA   +5 more
doaj  

Yak milk improves retinoic acid-induced osteoporosis by promoting intestinal calcium absorption

Journal of Dairy Science
: Yak milk is a unique nutritional quality milk with health-promoting benefits. In this study, we investigated the effect of yak milk on intestinal calcium absorption in mice with retinoic acid-induced osteoporosis (OP) and in the Caco-2 cell model ...
Torkun Mamet, Yanping Guo, Xiaotong Li, Jingru Yang, Bo Zhao   +4 more
doaj   +1 more source

Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice

Frontiers in Cellular Neuroscience, 2015
Kelch-like 1 (KLHL1) is a neuronal actin-binding protein that modulates voltage-gated CaV2.1 (P/Q-type) and CaV3.2 (α1H T-type) calcium channels; KLHL1 knockdown experiments (KD) cause down-regulation of both channel types and altered synaptic properties
Paula Patricia Perissinotti, Elizabeth G. Ethington, Erik eAlmazan, Elizabeth eMartínez-Hernández, Jennifer eKalil, Michael D. Koob, Erika S. Piedras-Renteria, Erika S. Piedras-Renteria   +7 more
doaj   +1 more source

Cryo-EM structure of a fungal mitochondrial calcium uniporter. [PDF]

, 2018
The mitochondrial calcium uniporter (MCU) is a highly selective calcium channel localized to the inner mitochondrial membrane. Here, we describe the structure of an MCU orthologue from the fungus Neosartorya fischeri (NfMCU) determined to 3.8 Å ...
Armache, Jean-Paul, Bai, Xiao-Chen, Cheng, Yifan, Jiang, Youxing, Lee, Changkeun, Mootha, Vamsi K, Nguyen, Nam X, Yang, Yi, Zeng, Weizhong   +8 more
core  

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Calcium channel blockers revisited [PDF]

, 2002
published_or_final_versio
Cheung, BMY, Kumana, CR
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source