Results 161 to 170 of about 3,623,918 (405)
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Advanced Biology, EarlyView.Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez +3 more
wiley +1 more source
Effect of oral administration of a new calcium channel blocking agent, bepridil on antipyrine clearance in man. [PDF]
, 1987 Christian Funck‐Brentano +4 more
openalex +1 more source
Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source
پزشکی بالینی ابن سینا, 2007 Background & Objective: Verapamil, nifedipine and diltiazem are calcium channel blockers widely used as a variety of cardiovascular ailment in humans. A number of studies have shown that calcium channel blockers have anticonvulsant effect in a range of ...
doaj
Recent advances in the development of T‐type calcium channel blockers for pain intervention
British Journal of Pharmacology, 2018 T. Snutch, G. Zamponi
semanticscholar +1 more source
Calcium: Mitochondria channel calcium [PDF]
Nature Reviews Molecular Cell Biology, 2011 openaire +3 more sources
Advanced Biology, EarlyView.Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams +7 more
wiley +1 more source
Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics
Advanced Engineering Materials, EarlyView.Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani +2 more
wiley +1 more source
Voltage-dependent inactivation of slow calcium channels in intact twitch muscle fibers of the frog. [PDF]
, 1989 G Cota, Enrico Stefani
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Deformation Behavior of La2O3‐Doped Copper during Equal Channel Angular Pressing
Advanced Engineering Materials, EarlyView.By additions of strengthening elements and/or structure optimization, the mechanical properties of copper can be increased while keeping favorable electric conductivity. By combining addition of La2O3 and processing by equal channel angular pressing, substructure development is achieved, leading to increase in microhardness to more than double the ...
Lenka Kunčická +2 more
wiley +1 more source