Results 61 to 70 of about 324,132 (168)

Does calcium channel blockade have a role in prevention of expression of sepsis in renal transplant recipients?

International Journal of Nephrology and Renovascular Disease, 2016
John A D’Elia,1–3 Ray E Gleason,3 Anthony P Monaco,2,3 Larry A Weinrauch,1–4 1Kidney and Hypertension Section, Joslin Diabetes Center, Boston, MA, 2Departments of Surgery and Medicine, Beth Israel Deaconess Medical Center, Boston, MA ...
D'Elia JA, Gleason RE, Monaco AP, Weinrauch LA   +3 more
doaj  

Targeting Ion Channels: Blockers Suppress Calcium Signals and Induce Cytotoxicity Across Medulloblastoma Cell Models

Bioengineering
Medulloblastoma (MB) groups 3 and 4 lack targeted therapies despite their dismal prognoses. Ion channels and pumps have been implicated in promoting MB metastasis and growth; however, their roles remain poorly understood. In this study, we repurposed FDA-
Darani Ashley Thammavongsa, Taylor N. Jackvony, Markus J. Bookland, Min D. Tang-Schomer   +3 more
doaj   +1 more source

Comparison of the Effect of Verapamil, Nifedipine and Diltiazem on Pentylenetetrazole-Induced Clonic Seizure Threshold in Mice

پزشکی بالینی ابن سینا, 2007
Background & Objective: Verapamil, nifedipine and diltiazem are calcium channel blockers widely used as a variety of cardiovascular ailment in humans. A number of studies have shown that calcium channel blockers have anticonvulsant effect in a range of ...

doaj  

Calcium: Mitochondria channel calcium [PDF]

Nature Reviews Molecular Cell Biology, 2011
openaire   +2 more sources

SH Oxidation Stimulates Calcium Release Channels (Ryanodine Receptors) From Excitable Cells

Biological Research, 2000
The effects of redox reagents on the activity of the intracellular calcium release channels (ryanodine receptors) of skeletal and cardiac muscle, or brain cortex neurons, was examined. In lipid bilayer experiments, oxidizing agents (2,2'-dithiodipyridine
CECILIA HIDALGO, RICARDO BULL, JUAN J MARENGO, CLAUDIO F PÉREZ, PAULINA DONOSO   +4 more
doaj  

A Case of Voltage-Gated Calcium Channel and TG6 Antibody-Positive Cerebellar Ataxia. [PDF]

Case Rep Neurol Med
Cifelli A, Butt Z, Cifelli E, Hadjivassiliou M.   +3 more
europepmc   +1 more source

Engineering of genetically encoded programmable calcium channel inhibitory binders. [PDF]

Nat Commun
Liu X, Ali S, Lan TH, Wang D, McKee B, Nonomura T, Liu S, Zhao F, Zhu MX, Huang Y, Deng Q, Ma G, Zhou Y.   +12 more
europepmc   +1 more source

Verapamil mitigates chloride and calcium bi-channelopathy in a myotonic dystrophy mouse model

The Journal of Clinical Investigation
Myotonic dystrophy type 1 (DM1) involves misregulated alternative splicing for specific genes. We used exon or nucleotide deletion to mimic altered splicing of genes central to muscle excitation-contraction coupling in mice.
Lily A. Cisco, Matthew T. Sipple, Katherine M. Edwards, Charles A. Thornton, John D. Lueck   +4 more
doaj   +1 more source

Determinants of calcium channel blocker-induced gingival hyperplasia among patients undergoing peritoneal dialysis. [PDF]

BMC Oral Health
Chen N, Fu L, Chu R, Xiao D, Ma Y, Tian N.   +5 more
europepmc   +1 more source

Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity. [PDF]

Drug Dev Res
Koçak Aslan E, Lam K, Huang S, Coşkun GP, Karagüzel A, Denzinger K, Birgül K, Ülgen M, Nafie JW, Şahin O, Armstrong DW, Zamponi GW, Wolber G, Gündüz MG.   +13 more
europepmc   +1 more source