Results 41 to 50 of about 324,132 (168)

Role of the TRPM4 Channel in Cardiovascular Physiology and Pathophysiology

open access: yesCells, 2018
The transient receptor potential cation channel subfamily M member 4 (TRPM4) channel influences calcium homeostasis during many physiological activities such as insulin secretion, immune response, respiratory reaction, and cerebral vasoconstriction. This
Chen Wang, Keiji Naruse, Ken Takahashi
doaj   +1 more source

Evaluation of prescription pattern of anti - Hypertensive drugs in Urban population of Hyderabad

open access: yesMRIMS Journal of Health Sciences, 2014
Knowledge of existing prescription patterns in the treatment of hypertension can provide useful information for improving clinical practice in this field.
M Jamuna Rani, G Jyothsna, Rohit Singh
doaj   +1 more source

Calcium Channel Blockers and Hypertension

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2014
Effective treatment of high blood pressure (BP) represents a key strategy for reducing the burden of hypertension-related cardiovascular and renal diseases. In spite of these well-established concepts, hypertension remains poorly controlled worldwide. In order to improve BP control in patients with hypertension, several interventions have been proposed,
TOCCI, GIULIANO   +6 more
openaire   +3 more sources

Calcium channels and migraine

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2013
Missense mutations in CACNA1A, the gene that encodes the pore-forming α1 subunit of human voltage-gated Ca(V)2.1 (P/Q-type) calcium channels, cause a rare form of migraine with aura (familial hemiplegic migraine type 1: FHM1). Migraine is a common disabling brain disorder whose key manifestations are recurrent attacks of unilateral headache that may be
openaire   +5 more sources

Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC

open access: yesMolecular Brain, 2019
This study describes the functional interaction between Cav3.2 calcium channels and the Epithelial Sodium Channel (ENaC). β-ENaC subunits showed overlapping expression with endogenous Cav3.2 calcium channels in the thalamus and hypothalamus as detected ...
Agustin Garcia-Caballero   +7 more
doaj   +1 more source

The fourth-generation Calcium channel blocker: Cilnidipine

open access: yesIndian Heart Journal, 2013
Several classes of antihypertensive agents have been in clinical use, including diuretics, α-blockers, β-blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin II type 1 receptor blockers (ARB), and organic calcium channel blockers (CCBs).
K. Sarat Chandra, G. Ramesh
doaj   +1 more source

A Modern View on the Treatment for Acute Calcium Channel Blocker Poisoning

open access: yesНеотложная медицинская помощь
BACKGROUND. At the beginning of the 21st century, the structure of acute exotoxicoses changed, in particular, an increase in poisoning by drugs that mainly affect the cardiovascular system, including calcium channel blockers, was noted.
A. Yu. Simonova   +4 more
doaj   +1 more source

Calcium Channel Blockers

open access: yesMedical Clinics of North America, 1988
The calcium channel blockers initially were approved for the treatment of classical and variant angina pectoris. Recent studies indicate that these agents also are useful in such diverse conditions as pulmonary and systemic hypertension, hypertrophic cardiomyopathy, arrhythmias, asthma, Raynaud's syndrome, esophageal spasm, myometrial hyperactivity ...
openaire   +2 more sources

RyR1 Is Involved in the Control of Myogenesis

open access: yesCells
The RyR1 calcium release channel is a key player in skeletal muscle excitation–contraction coupling. Mutations in the RYR1 gene are associated with congenital myopathies.
Amandine Tourel   +5 more
doaj   +1 more source

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