Results 21 to 30 of about 625,880 (309)
Mitogens and Calcium Channels [PDF]
Physiology, 1997 Mitogens and, in particular, growth factors can induce changes in free intracellular Ca2+ concentration by opening voltage-independent cationic channels, with different degrees of Ca2+ selectivity. Recent work has provided preliminary insights into the nature of these channels and their role in the control of cell cycle progression.
LOVISOLO, Davide +3 more
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Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement
Cell Reports, 2020 Summary: The secreted protein calcium-activated chloride channel regulator 1 (CLCA1) utilizes a von Willebrand factor type A (VWA) domain to bind to and potentiate the calcium-activated chloride channel TMEM16A.
Kayla N. Berry, Tom J. Brett
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A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes [PDF]
, 2005 We investigated the role of small-conductance calcium-activated potassium (SK) and intermediate-conductance calcium-activated potassium channels in modulating sensory transmission from peripheral afferents into the rat spinal cord.
Bahia, PK +7 more
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The roles of the subunits in the function of the calcium channel [PDF]
, 1991 Dihydropyridine-sensitive voltage-dependent L-type calcium channels are critical to excitation-secretion and excitation-contraction coupling. The channel molecule is a complex of the main, pore-forming subunit alpha 1 and four additional subunits: alpha ...
Biel, Martin +5 more
core +1 more source
Physiology, 2017 In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on ...
Mohamed, Trebak, James W, Putney
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Identification of a Novel EF-Loop in the N-terminus of TRPM2 Channel Involved in Calcium Sensitivity
Frontiers in Pharmacology, 2018 As an oxidative stress sensor, transient receptor potential melastatin 2 (TRPM2) channel is involved in many physiological and pathological processes including warmth sensing, ischemia injury, inflammatory diseases and diabetes.
Yuhuan Luo +4 more
doaj +1 more source
Energetics of discrete selectivity bands and mutation-induced transitions in the calcium-sodium ion channels family [PDF]
, 2013 We use Brownian dynamics (BD) simulations to study the ionic conduction and valence selectivity of a generic electrostatic model of a biological ion channel as functions of the fixed charge Qf at its selectivity filter.
Eisenberg, Robert S. +4 more
core +2 more sources
Calcium Channel Blocker Overdose Simulation
MedEdPORTAL, 2015 Introduction Accidental poisoning and drug overdose are a common occurrence in the emergency medicine setting. Often it is unknown what substances the patient has taken.
Michael Maniaci +2 more
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Calcium channels for endocytosis [PDF]
The Journal of Physiology, 2014 Exocytosis and endocytosis need to be tightly balanced to keep cell surface area constant. This is of particular relevance for presynaptic terminals, where endocytosis needs to compensate for the ongoing exocytosis of synaptic vesicle to ultimately guarantee reliable synaptic transmission.
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Vacuolar calcium channels [PDF]
Journal of Experimental Botany, 2007 The central vacuole is the largest Ca2+ store in a mature plant cell. Ca2+ release from this store contributes to Ca2+-mediated intracellular signalling in a variety of physiological responses. However, the routes for vacuolar Ca2+ release are not well characterized.
I I, Pottosin, G, Schönknecht
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