Results 31 to 40 of about 324,132 (168)
Non-ionotropic voltage-gated calcium channel signaling
ChannelsVoltage-gated calcium channels (VGCCs) are the major conduits for calcium ions (Ca2+) within excitable cells. Recent studies have highlighted the non-ionotropic functionality of VGCCs, revealing their capacity to activate intracellular pathways ...
Michael Trus, Daphne Atlas
doaj +1 more source
Calcium channel blocker poisoning
Zdravniški Vestnik, 2005 Background: Calcium channel blockers act at L-type calcium channels in cardiac and vascular smooth muscles by preventing calcium influx into cells with resultant decrease in vascular tone and cardiac inotropy, chronotropy and dromotropy.
Miran Brvar +3 more
doaj
Calcium regulation of muscle spindle mechanosensory afferent function
Experimental PhysiologyExtracellular calcium is crucial for the normal function of muscle spindle sensory afferents. They express multiple calcium buffering proteins. Extracellular calcium is essential for recycling of synaptic‐like vesicles (SLVs) in the terminals and for the
Anna Simon +5 more
doaj +1 more source
Frontiers in Microbiology, 2016 The oomycete vegetable pathogen Phytophthora capsici causes significant losses of important vegetable crops worldwide. Calcium and other plant nutrients have been used in disease management of oomycete pathogens.
Peiqing Liu +7 more
doaj +1 more source
Calcium Channels and Calcium-Binding Proteins
International Journal of Molecular Sciences, 2023 Signals of nerve impulses are transmitted to excitatory cells to induce the action of organs via the activation of Ca2+ entry through voltage-gated Ca2+ channels (VGCC), which are classified based on their activation threshold into high- and low-voltage activated channels, expressed specifically for each organ [...]
openaire +2 more sources
Cost Analysis of Antihypertensive Therapy in the Hypertensive Patients
Journal of College of Medical Sciences-NepalBackground Hypertension is an established chronic disease with a huge economic burden to society so choosing cost effective medication is essential. Several medications are available and the decision lies in the prescriber so the generation of evidence ...
Sabita Paudel +3 more
doaj +1 more source
Experimental and Molecular Medicine, 2019 Cancer: chloride transport protein protects tumors A chloride channel, a membrane protein involved in chloride transport, indirectly regulates calcium signaling to protect cancer cells from free radicals and DNA damage.
Jae-Rin Lee +5 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2000 We propose a model of calcium channels that can explain most of their observed properties, including the anomalous mole fraction effect and mutation of the glutamate residues. The structure grossly resembles that of the KcsA potassium channel except for the presence of an extracellular vestibule and a shorter selectivity filter containing four ...
Corry, Ben +3 more
openaire +3 more sources
Journal of Pharmacological Sciences, 2011 .: Transforming growth factor beta-1 (TGF-β1) plays a critical role in progression of cardiac fibrosis, which may involve intracellular calcium change. We examined effects of efonidipine, a dual T-type and L-type calcium channel blocker (CCB), on TGF-β1 ...
Bai Lei +10 more
doaj +1 more source
Mediators of Inflammation, 2020 Recent studies have illuminated that blocking Ca2+ influx into effector cells is an attractive therapeutic strategy for lung injury. We hypothesize that T-type calcium channel may be a potential therapeutic target for acute lung injury (ALI).
Limei Wan +8 more
doaj +1 more source