Results 11 to 20 of about 2,159,124 (309)
Calcium, calcium channels, and calcium channel antagonists
Canadian Journal of Physiology and Pharmacology, 1990 Voltage-dependent Ca2+ channels are an important pathway for Ca2+ influx in excitable cells. They also represent an important site of action for a therapeutic group of agents, the Ca2+ channel antagonists. These drugs enjoy considerable use in the cardiovascular area including angina, some arrhythmias, hypertension, and peripheral vascular disorders ...
David J. Triggle
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Calcium channel blocker poisoning [PDF]
Zdravniški Vestnik, 2005 Background: Calcium channel blockers act at L-type calcium channels in cardiac and vascular smooth muscles by preventing calcium influx into cells with resultant decrease in vascular tone and cardiac inotropy, chronotropy and dromotropy.
Miran Brvar +3 more
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International Journal of Nephrology and Renovascular Disease, 2016 John A D’Elia,1–3 Ray E Gleason,3 Anthony P Monaco,2,3 Larry A Weinrauch,1–4 1Kidney and Hypertension Section, Joslin Diabetes Center, Boston, MA, 2Departments of Surgery and Medicine, Beth Israel Deaconess Medical Center, Boston, MA ...
D'Elia JA +3 more
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Frontiers in Cellular Neuroscience, 2023 How do neurons that implement cell-autonomous self-regulation of calcium react to knockout of individual ion-channel conductances? To address this question, we used a heterogeneous population of 78 conductance-based models of hippocampal pyramidal ...
Sunandha Srikanth +2 more
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International Journal of Nephrology and Renovascular Disease, 2017 Larry A Weinrauch,1–4 Jiankang Liu,1 Brian Claggett,1 Peter V Finn,1 Matthew R Weir,5 John A D’Elia2–4 1Cardiovascular Division, Brigham and Women’s Hospital, 2Kidney and Hypertension Section, Joslin Diabetes Center, 3Department ...
Weinrauch LA +5 more
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Structure and function of potassium and calcium channels [PDF]
, 2005 In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
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CLCA2 is a positive regulator of store-operated calcium entry and TMEM16A. [PDF]
PLoS ONE, 2018 The Chloride Channel Accessory (CLCA) protein family was first characterized as regulators of calcium-activated chloride channel (CaCC) currents (ICaCC), but the mechanism has not been fully established. We hypothesized that CLCAs might regulate ICaCC by
Aarushi Sharma +4 more
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The role of calcium channel blockers in wound healing [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Wound healing is a natural response to restore the injured tissue to normal. Wound healing is also complicated process involving different cellular, molecular and biochemical mechanisms and various types of cytokines and growth factors.
Hoda Mojiri-Forushani
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Renoprotective effect of calcium channel blockers [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2009 The advancing chronic renal failure is at most the consequence of secondary haemodynamic and metabolic factors as intraglomerular hypertension and glomerular hypertrophy.
Dimković Nada, Dimković Siniša
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Channels, 2023 One of nature’s exceptions was discovered when a Cav3 T-type channel was observed to switch phenotype from a calcium channel into a sodium channel by neutralizing an aspartate residue in the high field strength (HFS) +1 position within the ion ...
J. David Spafford
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