Data about the current approach to the choice of dual antihypertensive combinations in various clinical situations for treatment of hypertension are presented.
A. M. Shilov +3 more
doaj +3 more sources
Renin-angiotensin system (RAS) inhibitors and calcium channel blockers (CCB) are often used together in chronic kidney disease (CKD). The PubMed, EMBASE, and Cochrane Library databases were searched to identify randomized controlled trials (RCTs) in ...
Mingming Zhao +9 more
doaj +1 more source
Calcium Channel Blocker Overdose Simulation
Introduction Accidental poisoning and drug overdose are a common occurrence in the emergency medicine setting. Often it is unknown what substances the patient has taken.
Michael Maniaci +2 more
doaj +1 more source
Inhibition of Escherichia coli chemotaxis by omega-conotoxin, a calcium ion channel blocker [PDF]
Escherichia coli chemotaxis was inhibited by omega-conotoxin, a calcium ion channel blocker. With Tris-EDTA-permeabilized cells, nanomolar levels of omega-conotoxin inhibited chemotaxis without loss of motility.
Adler, Julius +2 more
core +3 more sources
Pre-injury beta blocker use does not affect the hyperdynamic response in older trauma patients
Purpose: Trauma dogma dictates that the physiologic response to injury is blunted by beta-blockers and other cardiac medications. We sought to determine how the pre-injury cardiac medication profile influences admission physiology and post-injury ...
David C Evans +8 more
doaj +1 more source
The fourth-generation Calcium channel blocker: Cilnidipine
Several classes of antihypertensive agents have been in clinical use, including diuretics, α-blockers, β-blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin II type 1 receptor blockers (ARB), and organic calcium channel blockers (CCBs).
K. Sarat Chandra, G. Ramesh
doaj +1 more source
Chronic beta-adrenoceptor blockade and human atrial cell electrophysiology: evidence of pharmacological remodelling [PDF]
<b>Objective:</b> Chronic beta-adrenoceptor antagonist (β-blocker) treatment reduces the incidence of reversion to AF in patients, possibly via an adaptive myocardial response.
Kane, K.A. +4 more
core +1 more source
Strategies for studying permeation at voltage-gated ion channels [PDF]
Voltage-dependent ion channels are presently thought to consist of several distinct functional regions: (a) activation gates, (b) inactivation gates, and permeation pathways.
Lester, Henry A.
core +1 more source
Use of drug therapy in the management of symptomatic ureteric stones in hospitalized adults (SUSPEND), a multicentre, placebo-controlled, randomized trial of a calcium-channel blocker (nifedipine) and an α-blocker (tamsulosin) : study protocol for a randomized controlled trial [PDF]
Peer reviewedPublisher ...
Anson, Ken +12 more
core +2 more sources
Diltiazem for clozapine-induced generalized hyperhidrosis [PDF]
Background Clozapine can be associated with significant side effects and tolerability issues. Hyperhidrosis occurs less commonly and is unanticipated by clinicians because of clozapine's significant anticholinergic activity.
Kenton Emma M. PharmD +2 more
doaj +1 more source

