Results 31 to 40 of about 464,946 (417)
Effect of nimodipine and flunarizine on neuromuscular function in mice [PDF]
, 2016 Background: Changes in the intracellular concentration of Ca2+ control a number of cellular and physiological processes, hormone secretion, and cell fate and gene expression.
Kaikade, Swapnil B., Pise, Nitin D.
core +3 more sources
JAMA Network Open, 2019 Key Points Question What is the risk of experiencing the prescribing cascade of treating dihydropyridine calcium channel blocker–induced lower-extremity edema with a loop diuretic?
S. Vouri +6 more
semanticscholar +1 more source
Rate-dependent effects of lidocaine on cardiac dynamics: Development and analysis of a low-dimensional drug-channel interaction model [PDF]
, 2021 State-dependent Na+ channel blockers are often prescribed to treat cardiac arrhythmias, but many Na+ channel blockers are known to have pro-arrhythmic side effects. While the anti and proarrhythmic potential of a Na+ channel blocker is thought to depend on the characteristics of its rate-dependent block, the mechanisms linking these two attributes are ...
arxiv +1 more source
Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC [PDF]
, 2022 TMEM16A, a calcium-activated chloride channel involved in multiple cellular processes, is a proposed target for diseases such as hypertension, asthma, and cystic fibrosis.
Dutzler, Raimund +2 more
core +1 more source
Journal of Infectious Diseases, 2018 No therapeutics are approved for the treatment of filovirus infections. Bepridil, a calcium channel blocker developed for treating angina, was identified as a potent inhibitor of filoviruses in vitro, including Ebola and Marburg viruses, and Ebola virus ...
Lisa Evans DeWald +15 more
semanticscholar +1 more source
Calcium Channel Blockers and Hypertension
Journal of Cardiovascular Pharmacology and Therapeutics, 2014 Effective treatment of high blood pressure (BP) represents a key strategy for reducing the burden of hypertension-related cardiovascular and renal diseases. In spite of these well-established concepts, hypertension remains poorly controlled worldwide.
TOCCI, GIULIANO +6 more
openaire +4 more sources
Diltiazem for clozapine-induced generalized hyperhidrosis [PDF]
Mental Health Clinician, 2023 Background Clozapine can be associated with significant side effects and tolerability issues. Hyperhidrosis occurs less commonly and is unanticipated by clinicians because of clozapine's significant anticholinergic activity.
Kenton Emma M. PharmD +2 more
doaj +1 more source
Hyperinsulinemia-euglycemia therapy: a useful tool in treating calcium channel blocker poisoning [PDF]
, 2006 Hyperinsulinemia-euglycemia (HIE) therapy, when initiated promptly and aggressively, may offer considerable advantages in the treatment of calcium channel blocker poisoning.
Boyer, Edward, Levine, Michael D
core +2 more sources
International Journal of Molecular Sciences, 2018 Immunosuppression may occur for a number of reasons related to an individual’s frailty, debility, disease or from therapeutic iatrogenic intervention or misadventure. A large percentage of morbidity and mortality in immunodeficient populations is related
J. D'Elia, L. Weinrauch
semanticscholar +1 more source
A small footprint couch‐top support device for image‐guided radiotherapy of heavy patients
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose Patients with body weights close to or above 400 lbs present unique challenges in radiation therapy since the weight limit of most treatment couches decreases as the couch‐top extends toward the treatment gantry. The purpose of this work was to develop a small footprint couch‐top support platform to safely perform image‐guided ...
Huixiao Chen +5 more
wiley +1 more source