Results 51 to 60 of about 464,946 (417)

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

Initial Antihypertensive Regimens in Newly Treated Patients: Real World Evidence From the OneFlorida+ Clinical Research Network

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Knowledge of real‐world antihypertensive use is limited to prevalent hypertension, limiting our understanding of how treatment evolves and its contribution to persistently poor blood pressure control. We sought to characterize antihypertensive
Steven M. Smith, Almut G. Winterstein, Matthew J. Gurka, Marta G. Walsh, Shailina Keshwani, Anne M. Libby, William R. Hogan, Carl J. Pepine, Rhonda M. Cooper‐DeHoff   +8 more
doaj   +1 more source

Treatment for calcium channel blocker poisoning: A systematic review

Clinical toxicology, 2014
Context. Calcium channel blocker poisoning is a common and sometimes life-threatening ingestion. Objective. To evaluate the reported effects of treatments for calcium channel blocker poisoning.
M. St-Onge, P. Dubé, S. Gosselin, Chantal Guimont, J. Godwin, P. Archambault, J. Chauny, A. Frenette, M. Darveau, N. L. Sage, J. Poitras, J. Provencher, D. N. Juurlink, R. Blais   +13 more
semanticscholar   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Evaluation of prescription pattern of anti - Hypertensive drugs in Urban population of Hyderabad

MRIMS Journal of Health Sciences, 2014
Knowledge of existing prescription patterns in the treatment of hypertension can provide useful information for improving clinical practice in this field.
M Jamuna Rani, G Jyothsna, Rohit Singh
doaj   +1 more source

Regulation of store-operated calcium entry [PDF]

arXiv, 2023
Plasma membrane calcium influx through ion channels is crucial for many events in cellular physiology. Cell surface stimuli lead to the production of inositol 1,4,5-trisphosphate (IP3), which binds to IP3 receptors in the endoplasmic reticulum (ER) to release calcium pools from the ER lumen.
arxiv  

Statin, Calcium Channel Blocker and Beta Blocker Therapy May Decrease the Incidence of Tuberculosis Infection in Elderly Taiwanese Patients with Type 2 Diabetes

International Journal of Molecular Sciences, 2015
Background: It is well known that diabetes mellitus impairs immunity and therefore is an independent risk factor for tuberculosis. However, the influence of associated metabolic factors, such as hypertension, dyslipidemia and gout has yet to be confirmed.
M. Lee, Kun-Der Lin, Wei-Hao Hsu, Hsiu-Ling Chang, Yi‐Hsin C. Yang, P. Hsiao, S. Shin   +6 more
semanticscholar   +1 more source

Activation of PAC1 receptors in rat cerebellar granule cells stimulates both calcium mobilization from intracellular stores and calcium influx through N-type calcium channels

Frontiers in Endocrinology, 2013
High concentrations of pituitary adenylate cyclase-activating polypeptide (PACAP) and a high density of PACAP binding sites have been detected in the developing rat cerebellum.
Magali eBasille-Dugay, Magali eBasille-Dugay, Magali eBasille-Dugay, Magali eBasille-Dugay, Hubert eVaudry, Hubert eVaudry, Hubert eVaudry, Hubert eVaudry, Alain eFournier, Alain eFournier, Bruno J. Gonzalez, Bruno J. Gonzalez, David eVaudry, David eVaudry, David eVaudry, David eVaudry   +15 more
doaj   +1 more source

Calcium-Related Genes Predicting Outcomes and Serving as Therapeutic Targets in Endometrial Cancer

Cells, 2022
Endometrial cancer (EC) is the most common gynecologic cancer with increasing incidence. The dysregulation of intracellular calcium plays a crucial role in cancer progression.
Ting Huang, Xuan Feng, Jiaqi Wang, Jingyi Zhou, Jianliu Wang   +4 more
doaj   +1 more source

Use of drug therapy in the management of symptomatic ureteric stones in hospitalized adults (SUSPEND), a multicentre, placebo-controlled, randomized trial of a calcium-channel blocker (nifedipine) and an α-blocker (tamsulosin) : study protocol for a randomized controlled trial [PDF]

, 2014
Peer reviewedPublisher ...
Anson, Ken, Burr, Jennifer, Kilonzo, Mary, Lam, Thomas, MacLennan, Graeme Stewart, McClinton, Sam, McDonald, Alison, McPherson, Gladys, N'Dow, James, Pickard, Robert, Starr, Kathryn, SUSPEND Study Group, Thomas, Ruth   +12 more
core   +2 more sources