Results 21 to 30 of about 341,374 (309)

Title: The L-type Ca2+ channel blocker nifedipine inhibits mycelial growth, sporulation, and virulence of Phytophthora capsici

Frontiers in Microbiology, 2016
The oomycete vegetable pathogen Phytophthora capsici causes significant losses of important vegetable crops worldwide. Calcium and other plant nutrients have been used in disease management of oomycete pathogens.
Peiqing Liu, jie gong, xueling ding, Yue Jiang, guoliang chen, benjin li, qiyong weng, Qinghe Chen   +7 more
doaj   +1 more source

Calcium channel blockers for primary Raynaud's phenomenon.

Cochrane Database of Systematic Reviews, 2016
BACKGROUND Calcium channel blockers are the most commonly prescribed drugs for people with primary Raynaud's phenomenon. Primary Raynaud's phenomenon is a common condition characterised by an exaggerated vasospastic response to cold or emotion ...
H. Ennis, M. Hughes, Marina E Anderson, J. Wilkinson, A. Herrick   +4 more
semanticscholar   +1 more source

Neuroprotective effects of blockers for T-type calcium channels

Molecular Neurodegeneration, 2009
Cognitive and functional decline with age is correlated with deregulation of intracellular calcium, which can lead to neuronal death in the brain.
Lei Debin, Baird Michelle A, Lin-Ye Avary, Wildburger Norelle C, Bao Jianxin   +4 more
doaj   +1 more source

Investigation of the Effects of Calcıum Channel Blockers with Cigarette Smoke Exposure to Nerve Healing at Peripheral Nerve Injuries

Genel Tıp Dergisi, 2022
Objective: A study was planned to investigate the effect of exposure to cigarette smoke and the effects of calcium channel blockers in experimentally induced sciatic nerve injuries. Material-Method: The sciatic nerve was cut on one side in all the groups,
Muhammed Nebil Selimoğlu, Mustafa Raşid Toksöz, Abit Aktaş, Funda Yiğit, Nedim Savacı   +4 more
doaj   +1 more source

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome

eLife, 2015
Calcium channel blockers (CCBs) are prescribed to patients with Marfan syndrome for prophylaxis against aortic aneurysm progression, despite limited evidence for their efficacy and safety in the disorder.
J. Doyle, A. J. Doyle, Nicole K Wilson, J. Habashi, D. Bedja, R. Whitworth, M. Lindsay, F. Schoenhoff, Loretha A Myers, N. Huso, S. Bachir, Oliver Squires, B. Rusholme, Hamid Ehsan, D. Huso, Craig J. Thomas, M. Caulfield, J. V. Van Eyk, D. Judge, H. Dietz, Carrie Williams Harry C Kira Kathryn W Jennifer Dianna M Farrar Ravekes Dietz Lurman Holmes Habashi Milewic, Harry C Andrew S Bart Lut Per Anders Luc Seema Salah A G Dietz McCallion Loeys Van Laer Eriksson Franco-Cer   +21 more
semanticscholar   +1 more source

The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension.

New England Journal of Medicine, 1992
BACKGROUND Primary pulmonary hypertension is a progressive, fatal disease of unknown cause. Vasodilator drugs have been used as a treatment, but their efficacy is uncertain.
S. Rich, E. Kaufmann, P. Levy
semanticscholar   +1 more source

Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers

Nature Communications, 2014
Autophagy deregulation during obesity contributes to the pathogenesis of diverse metabolic disorders. However, without understanding the molecular mechanism of obesity interference in autophagy, development of therapeutic strategies for correcting such ...
Hwan-Woo Park, Haeli Park, Ian A. Semple, I. Jang, Seung-Hyun Ro, Myungjin Kim, V. Cazares, E. Stuenkel, Jung-jae Kim, Jeong-Sig Kim, J. H. Lee   +10 more
semanticscholar   +1 more source

Calcium channel blockers for inhibiting preterm labour and birth.

Cochrane Database of Systematic Reviews, 2014
BACKGROUND Preterm birth is a major contributor to perinatal mortality and morbidity, affecting around 9% of births in high-income countries and an estimated 13% of births in low- and middle-income countries. Tocolytics are drugs used to suppress uterine
V. Flenady, A. Wojcieszek, D. Papatsonis, Owen M Stock, L. Murray, L. Jardine, B. Carbonne   +6 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Herbicidal properties of antihypertensive drugs: calcium channel blockers

Scientific Reports, 2021
Herbicide resistance is a worldwide problem in weed control. This prompts researchers to look for new modes of action to slow down the evolution of herbicide-resistant weeds.
Hannan Safiyyah Tan Sian Hui Abdullah, Poh Wai Chia, Dzolkhifli Omar, Tse Seng Chuah   +3 more
doaj   +1 more source