Results 41 to 50 of about 91,887 (263)
پزشکی بالینی ابن سینا, 2007 Background & Objective: Verapamil, nifedipine and diltiazem are calcium channel blockers widely used as a variety of cardiovascular ailment in humans. A number of studies have shown that calcium channel blockers have anticonvulsant effect in a range of ...
doaj
The Calcium Channel Blocker Controversy.
Hypertension Research, 1996 A major controversy about the safety of calcium channel blockers (CCBs) has arisen since the publication of a case-control study showing that hypertensives who suffered an acute myocardial infarction (MI) were more likely than hypertensives who had not had an MI to be taking one of these (short-acting) agents than other antihypertensive agents.
openaire +3 more sources
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
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Comparison between The Effect of Progesterone and Calcium Channel blockers in Control of Threatened Preterm Labor [PDF]
Al-Azhar International Medical JournalBackground: If the cervix begins to dilate and efface before the 37th week of gestation, it is considered preterm labor. This condition is characterized by strong, frequent uterine contractions.
Ahmed Khalil +2 more
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Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Long-term effects of antihypertensive medications on bone mineral density in men older than 55 years
Clinical Interventions in Aging, 2014 Kamil Serkan Ağaçayak,1 Sedat Güven,2 Mahmut Koparal,1 Nedim Güneş,1 Yusuf Atalay,3 Serhat Atilgan11Department of Oral and Maxillofacial Surgery, 2Department of Prosthodontics, School of Dentistry, University of Dicle, Diyarbakir, Turkey;
Ağaçayak KS +5 more
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A Rare Case Report of Amlodipine-Induced Gingival Enlargement and Review of Its Pathogenesis
Case Reports in Dentistry, 2013 Gingival enlargement is a common clinical feature of gingival and periodontal diseases. It is an unwanted side effect of certain systemic drugs given for nondental treatment.
Sanjeev Joshi, Sucheta Bansal
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Journal of Pharmaceutical Health Care and Sciences, 2018 Background Falls are a common but serious problem in older adults, and may lead to fractures and bleeding. As many factors, such as medication, aging, and comorbid diseases may simultaneously affect fall-related adverse events (AEs) in older adults, we ...
Haruna Hatahira +13 more
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Managing new-onset atrial fibrillation in critically ill patients: a systematic narrative review
BMJ Open, 2020 Objectives The aim of this review is to summarise the latest evidence on efficacy and safety of treatments for new-onset atrial fibrillation (NOAF) in critical illness.Participants Critically ill adult patients who developed NOAF during admission.Primary
Oliver C Redfern +5 more
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