Results 151 to 160 of about 3,593,980 (394)

Effects of axotomy on calcium influx in reticulospinal neurons of larval lamprey [abstract] [PDF]

, 2007
only availableThe lamprey is a prime example of the remarkable axonal regeneration that can occur in lower vertebrates. Previous studies showed that spinal cord transected lamprey recover normal locomotor behavior in about 8 weeks (McClellan, 1998). With
Cozad, Matthew, McClellan, Andrew
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Functional properties of the Ca_v1.2 calcium channel activated by calmodulin in the absence of α₂δ subunits [PDF]

, 2009
Arippa Ravindran, Evgeny Kobrinsky, Qi Zong Lao, Nikolai M. Soldatov   +3 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The multifaceted role of calcium signaling dynamics in neural cell proliferation and gliomagenesis

AIMS Biophysics
Calcium (Ca2+) signaling plays a pivotal role in coordinating neural stem cell (NSC) proliferation across various cell cycle stages, regulating immediate early gene transcription, and governing processes like quiescence and cell division.
Ola A Al-Ewaidat , Sopiko Gogia, Valiko Begiashvili, Moawiah M Naffaa   +3 more
doaj   +1 more source

Calcium‐activated potassium channels in goldfish hair cells. [PDF]

, 1994
Izumi Sugihara
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Control of KCa Channels by Calcium Nano/Microdomains [PDF]

, 2008
Bernd Fakler, John P. Adelman
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

The Glutathione Transferase Structural Family Includes a Nuclear Chloride Channel and a Ryanodine Receptor Calcium Release Channel Modulator [PDF]

, 2001
Angela F. Dulhunty, Peter W. Gage, Suzanne M. Curtis, Gareth Chelvanayagam, Philip G. Board   +4 more
openalex   +1 more source