Results 41 to 50 of about 569,388 (236)

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]

, 2011
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bingham, Chen, Clinton, Cross, Cummings, de Vogel, Denis E. Corpet, Douglass, Fabrice H.F. Pierre, Grant, Leuratti, Marnett, Mirvish, Nadia M. Bastide, Nauss, Nutter, Parnaud, Pierre, Pierre, Sandhu, Sawa, Schwartz, Sesink, Shuker, Sinha   +24 more
core   +3 more sources

Calcium L-edge XANES study of some calcium compounds

Journal of Synchrotron Radiation, 2001
The Ca L3,2-edge XANES spectra of six calcium salts have been measured in both total electron and fluorescence yields using a high-resolution spherical grating monochromator. The compounds investigated were; CaF2, CaCO3, CaCl2 ˙2H2O, calcium phosphate, calcium glycerophosphate and calcium gluconate.
S. J. Naftel, Tsun-Kong Sham, Y. M. Yiu, B. W. Yates   +3 more
openaire   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]

, 2010
Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Belbraouet, Bruce, Bull, Cross, Denis E. Corpet, Diane Bahuaud, Fabrice H. F. Pierre, Karkare, Nathalie Naud, Ossama Allam, Pierre, Sesink, Sinha, Sylviane Taché, Van den Berg   +14 more
core   +3 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Influence of the structural modulations and the Chain-ladder interaction in the $Sr\_{14-x}Ca\_{x}Cu\_{24}O\_{41}$ compounds

, 2006
We studied the effects of the incommensurate structural modulations on the ladder subsystem of the $Sr\_{14-x}Ca\_{x}Cu\_{24}O\_{41}$ family of compounds using ab-initio explicitly-correlated calculations.
A. Chakrabartty, Alex J. Levine, B. Chakrabarti, Buddhapriya Chakrabarti, D. Poland, E. Evans, J. S. Mills, M. E. Fisher, M. Rief, O. Kratky, P. Debye, P. M. Chaikin, S. Smith, T. M. Birshtein   +13 more
core   +2 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Meat and cancer: haemoglobin and haemin in a low calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats [PDF]

, 2003
High intake of red meat, but not of white meat, is associated with an increased risk of colon cancer. However, red meat does not promote cancer in rodents.
Corpet, Denis E., Petit, Claude, Pierre, Fabrice, Taché, Sylviane, Van der Meer, Roleof   +4 more
core   +3 more sources

Compounds of the Structural Type of Calcium Titanate [PDF]

Nature, 1945
IN a previous communication1, it was recorded that precision X-ray powder methods with a large-diameter camera show that the structure of nickel oxide is not strictly cubic, but only pseudo-cubic. Splitting of some of the X-ray reflexions into more than one component is explained if a small distortion of the cubic lattice along an octahedral axis is ...
openaire   +1 more source