Results 11 to 20 of about 1,096,111 (252)
Artificial Egg Activation Using Calcium Ionophore [PDF]
Seminars in Reproductive Medicine, 2021 AbstractArtificial oocyte activation, most commonly using calcium ionophore, is a treatment add-on utilized to avoid recurrence of abnormally low or total failed fertilization following in vitro fertilization/intracytoplasmic sperm injection. It aims to modify defective physiological processes, specifically calcium-mediated cell signaling that are ...
Ahmed Attia +2 more
openaire +5 more sources
Usnic acid as calcium ionophore and mast cells stimulator
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2020 Usnic acid (UA), a secondary lichen metabolite, has long been popular as one of natural fat-burning dietary supplements. Similar to 2,4-dinitrophenol, the weight-loss effect of UA is assumed to be associated with its protonophoric uncoupling activity.
Maria A, Chelombitko +7 more
openaire +3 more sources
Activation of Sea-Urchin Eggs by a Calcium Ionophore [PDF]
Proceedings of the National Academy of Sciences, 1974 Micromolar amounts of the divalent ionophore A23187 can activate echinoderm eggs. The activations by ionophore A23187 were examined in terms of membrane elevation, the program of membrane conductance changes, the respiratory burst, and the increases in protein and DNA synthesis which normally accompany activation by sperm.
R A, Steinhardt, D, Epel
openaire +3 more sources
Effect of heparin, caffeine and calcium ionophore A23187 on in vitro induction of the acrosome reaction of fresh ram spermatozoa [PDF]
Asian Pacific Journal of Reproduction, 2016 Objective: To determine the effect of different concentrations of heparin, caffeine or calcium ionophore and incubation time on motility, hyperactivity (HA) and acrosome reaction (AR) of ram sperm in vitro.
K.H. El-Shahat +3 more
doaj +2 more sources
Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models. [PDF]
Sci Rep, 2016 Mammalian sperm acquire fertilizing capacity in the female tract in a process called capacitation. At the molecular level, capacitation requires protein kinase A activation, changes in membrane potential and an increase in intracellular calcium ...
Navarrete FA +12 more
europepmc +2 more sources
Nimodipine promotes neurite outgrowth and protects against neurotoxicity in PC12 cells [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Nimodipine is an L-type voltage-dependent calcium channel (VDCC) antagonist. However, the actions of nimodipine except calcium blocking are poorly understood. This study aimed to investigate the effect of nimodipine on neurite outgrowth and
Miduki Kusakabe, Yasushi Hasegawa
doaj +1 more source
Effect of calcium ionophore A23187 on the sperm in intracytoplasmic sperm injection. [PDF]
Journal of Bioscience and Applied Research, 2016 The present study evaluated the effect of calcium ionophore A23187 on sperm in intracytoplasmic sperm injection (ICSI) cycles using sperm from different sources.
Abd El-Wahab El-Ghareeb +4 more
doaj +1 more source
Mitogenic Properties of a Calcium Ionophore, A23187 [PDF]
Proceedings of the National Academy of Sciences, 1974 A23187 is a carboxylic antibiotic that selectively transfers calcium, magnesium, and other divalent cations across biologic membranes. This ionophore was found to produce morphologic blast transformation, DNA synthesis, and mitosis in human lymphocytes. Several hours of ionophore-cell contact were necessary to produce optimal mitogenesis.
J R, Luckasen, J G, White, J H, Kersey
openaire +2 more sources
PROTECTIVE EFFECTS OF CALCIUM ANTAGONIST (NITRENDIPINE) ON CALCIUM IONOPHORE A23187-INDUCED LIVER CELL INJURY [PDF]
, 1991 Calcium ionophore A23187-induced liver damage was studied in perfused rat liver and isolated hepatocytes. Two groups of calcium antagonists, dihydropyridine-type and nondihydropyridine-type, were examined for their protective effects on A23187-induced ...
Shunho, MATSUDA
core +2 more sources
Myosin V and iNOS expression is enhanced in J774 murine macrophages treated with IFN-gamma [PDF]
Brazilian Journal of Medical and Biological Research, 2001 Actin-based motor protein requirements and nitric oxide (NO) production are important features of macrophage activity during phagocytosis or microbicidal processes.
D.S. Reis +3 more
doaj +1 more source