Oxidative stress impairs the meat quality of broiler by damaging mitochondrial function, affecting calcium metabolism and leading to ferroptosis. [PDF]
Anim Biosci, 2022 Objective This work was conducted to investigate the effects of oxidative stress on meat quality, mitochondrial function, calcium metabolism and ferroptosis of broilers.
Chen Z +5 more
europepmc +2 more sources
Calcium Overload and Mitochondrial Metabolism
Biomolecules, 2022 Mitochondria calcium is a double-edged sword. While low levels of calcium are essential to maintain optimal rates of ATP production, extreme levels of calcium overcoming the mitochondrial calcium retention capacity leads to loss of mitochondrial function.
Lauren L. Walkon +2 more
semanticscholar +1 more source
Identification of small molecules as novel anti-adipogenic compounds based on Connectivity Map
Frontiers in Endocrinology, 2022 Several physiological and pathological conditions such as aging, obesity, diabetes, anorexia nervosa are associated with increased adipogenesis in the bone marrow.
Shuang Zhang +5 more
doaj +1 more source
Functional Effects of Prebiotic Fructans in Colon Cancer and Calcium Metabolism in Animal Models. [PDF]
Biomed Res Int, 2017 Inulin-type fructans are polymers of fructose molecules and are known for their capacity to enhance absorption of calcium and magnesium, to modulate gut microbiota and energy metabolism, and to improve glycemia.
Rivera-Huerta M +8 more
europepmc +2 more sources
HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis
Stem Cell Research & Therapy, 2023 Background Recent evidence suggests that accumulation of marrow adipose tissue induced by aberrant lineage allocation of bone marrow-derived mesenchymal stromal cells (BMSCs) contributes to the pathophysiologic processes of osteoporosis.
Shuang Zhang +4 more
doaj +1 more source
BMJ Open, 2021 Introduction Hypercalcaemia of malignancy (HCM) is the second most common cause of hypercalcaemia and is associated with significant morbidity and mortality.
M. Hassan Murad +5 more
doaj +1 more source
Physical Activity-Dependent Regulation of Parathyroid Hormone and Calcium-Phosphorous Metabolism
International Journal of Molecular Sciences, 2020 Exercise perturbs homeostasis, alters the levels of circulating mediators and hormones, and increases the demand by skeletal muscles and other vital organs for energy substrates. Exercise also affects bone and mineral metabolism, particularly calcium and
G. Lombardi +3 more
semanticscholar +1 more source
Growth pattern in children with X-linked hypophosphatemia treated with burosumab and growth hormone
Orphanet Journal of Rare Diseases, 2022 Background X-linked hypophosphatemia (XLH) is characterized by increased serum concentrations of fibroblast growth factor 23 (FGF23), hypophosphatemia and insufficient endogenous synthesis of calcitriol.
Diana-Alexandra Ertl +11 more
doaj +1 more source
Frontiers in Endocrinology, 2021 Mutations in CYP24A1 (vitamin D 24-hydroxylase) and SLC34A1 (renal phosphate transporter NPT2a) cause autosomal recessive Infantile Hypercalcemia type 1 and 2, illustrating links between vitamin D and phosphate metabolism.
Arnaud Molin +26 more
doaj +1 more source
Disorders of Calcium and Phosphorus Metabolism and the Proteomics/Metabolomics-Based Research
Frontiers in Cell and Developmental Biology, 2020 Since calcium and phosphorus play vital roles in a multitude of physiologic systems, disorders of calcium and phosphorus metabolism always lead to severe consequences such as skeletal-related and cardiovascular morbidity, or even life-threatening ...
Meiheng Sun +9 more
semanticscholar +1 more source