Results 31 to 40 of about 2,493,792 (352)

Genetic variants of calcium and vitamin D metabolism in kidney stone disease

open access: yesNature Communications, 2019
Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a heritability of ~45–60%. We present genome-wide association studies in British and Japanese populations and a trans-ethnic meta-analysis that include 12,123 ...
S. Howles   +15 more
semanticscholar   +1 more source

Identification of Three Early Phases of Cell-Fate Determination during Osteogenic and Adipogenic Differentiation by Transcription Factor Dynamics

open access: yesStem Cell Reports, 2017
Summary: Age-related skeletal degeneration in patients with osteoporosis is characterized by decreased bone mass and occurs concomitant with an increase in bone marrow adipocytes.
Jeroen van de Peppel   +5 more
doaj   +1 more source

Effect of Altered Calcium Metabolism on Orthodontic Tooth Movement: a Systematic Review [PDF]

open access: yesIranian Journal of Orthodontics, 2022
Aim: The aim of this study was to analyze and synthesize data from animal research on the impact of hormones and their synthetic derivatives on orthodontic tooth movement by altering calcium metabolism.Methods: Eight databases were scanned electronically,
Pasupureddi Keerthana   +3 more
doaj   +1 more source

Derangement of calcium metabolism in diabetes mellitus: negative outcome from the synergy between impaired bone turnover and intestinal calcium absorption

open access: yesJournal of Physiological Sciences, 2016
Both types 1 and 2 diabetes mellitus (T1DM and T2DM) are associated with profound deterioration of calcium and bone metabolism, partly from impaired intestinal calcium absorption, leading to a reduction in calcium uptake into the body. T1DM is associated
Kannikar Wongdee   +2 more
semanticscholar   +1 more source

Parathyroids and calcium metabolism [PDF]

open access: yesExperimental Biology and Medicine, 1918
The experiments reported in this article are in full agreement with the facts known about the action of Ca and Mg salts in tetanic animals. In the concentrations used here both Ca lactate and Mg lactate suppressed the muscular convulsions in the tetanic salamander larvæ. The Mg lactate, however, appears to be more effective than the Ca lactate.
openaire   +2 more sources

Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling

open access: yesNature Communications, 2018
The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH) in contributing to hepatocellular carcinoma (HCC) remain undefined.
J. Q. Liang   +14 more
semanticscholar   +1 more source

Calcium phosphate precipitation inhibits mitochondrial energy metabolism

open access: yesPLoS Comput. Biol., 2019
Early studies have shown that moderate levels of calcium overload can cause lower oxidative phosphorylation rates. However, the mechanistic interpretations of these findings were inadequate.
Sathyavani Malyala   +3 more
semanticscholar   +1 more source

Increased prevalence of overweight and obesity in children with X-linked hypophosphatemia

open access: yesEndocrine Connections, 2020
Background/aim: X-linked hypophosphatemia (XLH) is a rare disease characterized by low phosphate levels. Scientific evidence points to a link between h ypophosphatemia and obesity in general population. The aim of our longitudinal observational study was
Volha V Zhukouskaya   +11 more
doaj   +1 more source

Seipin regulates lipid homeostasis by ensuring calcium‐dependent mitochondrial metabolism

open access: yesEMBO Journal, 2018
Seipin, the gene that causes Berardinelli‐Seip congenital lipodystrophy type 2 (BSCL2), is important for adipocyte differentiation and lipid homeostasis. Previous studies in Drosophila revealed that Seipin promotes ER calcium homeostasis through the Ca2+‐
Long Ding   +9 more
semanticscholar   +1 more source

The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue

open access: yesBiomolecules, 2021
Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium–phosphorus homeostasis.
Żaneta Ciosek   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy