Results 1 to 10 of about 2,340,161 (352)

Preparation and properties of polyvinyl alcohol/calcium phosphate composite bone cement [PDF]

Journal of International Medical Research
Background The inherent brittleness of calcium phosphate cement has limited its clinical application. Polyvinyl alcohol fibers have been demonstrated to enhance the tensile toughness of concrete matrices.
Shengliang He, Yi He, Xuancheng Fang, Shiwen Liao, Jinhuang Xu, Minhui He, Cong Zheng, Lifen Zhou, Dawei Xu, Jianrong Huang   +9 more
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Diagnostic yield of bone fragility gene panel sequencing in children and young adults referred for idiopathic primary osteoporosis at a single regional reference centre

Bone Reports, 2022
Aim: To describe the presenting features, bone characteristics and molecular genetics in a large monocentric cohort of children and young adults with idiopathic primary osteoporosis.
Coline Rouleau, Margaux Malorie, Corinne Collet, Valérie Porquet-Bordes, Isabelle Gennero, Sanaa Eddiry, Michel Laroche, Jean Pierre Salles, Guillaume Couture, Thomas Edouard   +9 more
doaj   +1 more source

Growth pattern in children with X-linked hypophosphatemia treated with burosumab and growth hormone

Orphanet Journal of Rare Diseases, 2022
Background X-linked hypophosphatemia (XLH) is characterized by increased serum concentrations of fibroblast growth factor 23 (FGF23), hypophosphatemia and insufficient endogenous synthesis of calcitriol.
Diana-Alexandra Ertl, Justin Le Lorier, Andreas Gleiss, Séverine Trabado, Candace Bensignor, Christelle Audrain, Volha Zhukouskaya, Régis Coutant, Jugurtha Berkenou, Anya Rothenbuhler, Gabriele Haeusler, Agnès Linglart   +11 more
doaj   +1 more source

Prenatal features and neonatal management of severe hyperparathyroidism caused by the heterozygous inactivating calcium-sensing receptor variant, Arg185Gln: A case report and review of the literature

Bone Reports, 2021
Background: Loss-of-function variants in the calcium-sensing receptor (CASR) gene are known to be involved in a clinical spectrum ranging from asymptomatic familial hypocalciuric hypercalcemia (FHH) to neonatal severe hyperparathyroidism (NSHPT ...
Marion Aubert-Mucca, Charlotte Dubucs, Marion Groussolles, Julie Vial, Edouard Le Guillou, Valerie Porquet-Bordes, Eric Pasmant, Jean-Pierre Salles, Thomas Edouard   +8 more
doaj   +1 more source

Growth hormone treatment improves final height in children with X-linked hypophosphatemia

Orphanet Journal of Rare Diseases, 2022
Background/aim Despite optimal conventional treatment (oral phosphate supplements and active vitamin D analogs), about 40–50% of children with well-controlled X-linked hypophosphatemia (XLH) show linear growth failure, making them less likely to achieve ...
Julia André, Volha V. Zhukouskaya, Anne-Sophie Lambert, Jean-Pierre Salles, Brigitte Mignot, Claire Bardet, Catherine Chaussain, Anya Rothenbuhler, Agnès Linglart   +8 more
doaj   +1 more source

Circulating autotaxin levels in healthy teenagers: Data from the Vitados cohort

Frontiers in Pediatrics, 2023
Autotaxin (ATX) is a secreted enzyme with a lysophospholipase D activity, mainly secreted by adipocytes and widely expressed. Its major function is to convert lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), an essential bioactive lipid ...
Marie-Noëlle Méaux, Marie-Noëlle Méaux, Marie-Noëlle Méaux, Maitena Regnier, Maitena Regnier, Maitena Regnier, Aurélie Portefaix, Olivier Borel, Candide Alioli, Olivier Peyruchaud, Mélanie Legrand, Mélanie Legrand, Mélanie Legrand, Justine Bacchetta, Justine Bacchetta, Justine Bacchetta, Justine Bacchetta   +16 more
doaj   +1 more source

Oral health-related quality of life in patients with X-linked hypophosphatemia: a qualitative exploration

Endocrine Connections, 2022
Introduction: X-linked hypophosphatemia (XLH) is a rare, hereditary, and lifelong phosphate-wasting disorder characterized by rickets in childhood and impaired teeth mineralization.
Caroline Nguyen, Elisabeth Celestin, Delphine Chambolle, Agnès Linglart, Martin Biosse Duplan, Catherine Chaussain, Lisa Friedlander   +6 more
doaj   +1 more source

Impact of Early Conventional Treatment on Adult Bone and Joints in a Murine Model of X-Linked Hypophosphatemia

Frontiers in Cell and Developmental Biology, 2021
X-linked hypophosphatemia (XLH) is the most common form of genetic rickets. Mainly diagnosed during childhood because of growth retardation and deformities of the lower limbs, the disease affects adults with early enthesopathies and joint structural ...
Axelle Cauliez, Volha V. Zhukouskaya, Volha V. Zhukouskaya, Volha V. Zhukouskaya, Stéphane Hilliquin, Stéphane Hilliquin, Jérémy Sadoine, Lotfi Slimani, Corinne Miceli-Richard, Karine Briot, Karine Briot, Agnès Linglart, Agnès Linglart, Catherine Chaussain, Catherine Chaussain, Catherine Chaussain, Claire Bardet   +16 more
doaj   +1 more source

Development of Enthesopathies and Joint Structural Damage in a Murine Model of X-Linked Hypophosphatemia

Frontiers in Cell and Developmental Biology, 2020
X-linked hypophosphatemia (XLH) is characterized by rickets and osteomalacia, caused by inactivating mutations in the Phosphate-regulating endopeptidase homolog X-linked (PHEX) gene.
Carole-Anne Faraji-Bellée, Axelle Cauliez, Benjamin Salmon, Benjamin Salmon, Olivier Fogel, Volha Zhukouskaya, Volha Zhukouskaya, Aurélie Benoit, Thorsten Schinke, Christian Roux, Agnès Linglart, Agnès Linglart, Agnès Linglart, Corinne Miceli-Richard, Catherine Chaussain, Catherine Chaussain, Catherine Chaussain, Karine Briot, Karine Briot, Claire Bardet   +19 more
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Longitudinal Effects of Serum Calcium and Phosphate Levels and Their Ratio on Incident Ischemic Heart Disease among Korean Adults

Biomolecules, 2022
Serum calcium and phosphate levels are controlled by a regulatory system, but their individual concentration tendencies and interactions may affect long-term vascular health. This study aimed to assess the effects of serum calcium and phosphate levels on
Dong Hyuk Jung, Byoungjin Park, Yong Jae Lee   +2 more
doaj   +1 more source