Results 121 to 130 of about 492,665 (311)
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Control of mineral scaling in power plant recirculating cooling systems using treated municipal wastewater [PDF]
The global energy demand is projected to increase by 77% from 2006 to 2030 along with a projected 38% increase in freshwater withdrawal for cooling in power industry. Finding alternative sources of water for cooling has become essential for future energy
Wenshi, Liu
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Reinforcement of sol-gel processed calcium phosphate cement using functionalised CNTs
Calcium phosphate is bioactive, biodegradable graft material with excellent biological properties. However, its low strength limits its use to only non-stress application1 .
Natesan, Kiruthika +3 more
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Calcium phosphate precipitation modeling in a pellet reactor [PDF]
The calcium phosphate precipitation in a pellet reactor can be evaluated by two main parameters: the phosphate conversion ratio and the phosphate removal efficiency. The conversion ratio depends mainly on the pH. The pellet reactor efficiency depends not
Cabassud, Michel +3 more
core
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Calcium phosphate materials are widely used in medical field as bone grafts and scaffolds, due to biocompatibility and chemical similarity with natural mineral phase of bone.
Ločs, Jānis +4 more
core
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

