Results 111 to 120 of about 100,161 (306)

Characterization and Processing of Phosphate Rock as a Raw Material for Potential Use as Biomaterials

open access: yesCiencia e Ingeniería Neogranadina
Seventy-five percent of the phosphate rock extracted is used for the production of phosphoric acid. However, during the leaching process, it is also possible to dissolve calcium compounds, allowing for the extraction of phosphorus and calcium ions from ...
Gloria Soto Calle   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

New Na+,Mg2+,Zn2+ -containing hydroxyapatite/ZrO2 composites: preparation, mechanic properties and cytotoxicity

open access: yesBMC Chemistry
Firstly apatite-type carbonated calcium phosphate and biphasic calcium phosphates (mixture of phases based on Ca10(PO4)6(OH)2 and β-Ca3(PO4)2 with weight ratio 60 : 40%) which contained the trace elements complex (Na+, Mg2+, Zn2+) were obtained from ...
N. Strutynska   +6 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Movement of Trace Elements During Residence in the Antarctic Ice: a Laboratory Simulation [PDF]

open access: yes, 1991
Recent work has determined that differences in the trace element distribution between Antarctic eucrites and non-Antarctic eucrites may be due to weathering during residence in the ice, and samples that demonstrate trace element disturbances do not ...
Strait, Melissa M.
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Determination of some blood parameters during pregnancy and lactation periods in healthy akkaraman kangal ewes [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Aim: The aim of this study to investigate the influence in reproductive status on the serum concentration of biochemical markers and some macro elements in sera of Akkaraman Kangal ewes during late pregnancy and early lactation.
Nazli Ercan   +2 more
doaj  

Research of the structure of gallstones by IR-spectroscopy method [PDF]

open access: yes, 2018
The composition of gallstones was studied by IR spectroscopy. It is shown that it is possible to establish the presence in the gallstones of such compounds as bilirubin and its salts, calcium phosphates, calcium carbonate, which are present in them in ...
Пичугина, А. А.
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

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