Results 111 to 120 of about 1,747,741 (337)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Determination of some blood parameters during pregnancy and lactation periods in healthy akkaraman kangal ewes [PDF]
Eurasian Journal of Veterinary SciencesAim: The aim of this study to investigate the influence in reproductive status on the serum concentration of biochemical markers and some macro elements in sera of Akkaraman Kangal ewes during late pregnancy and early lactation.
Nazli Ercan +2 more
doaj
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Polylactic Acid - Calcium Phosphates Composites
Calcium phosphates (CaP) have excellent biomaterial properties due to their similarity to the inorganic component of the bone matrix. However, CaP clinical application is restricted due to their inherent brittleness and poor shepe ability.
Sokolova, Marina +3 more
core
Controlled crystallisation of calcium phosphate and calcium carbonate via bio-inspired approaches: additives and confinement [PDF]
, 2013 This thesis describes the investigation of the two bio-inspired approaches, confinement and additives, to manipulate the crystallization of calcium carbonate and calcium phosphate.
Cantaert, Bram
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2008 PhDAccidents, surgery and disease often result in the use of biomimetic materials that can replace human hard tissue and calcium phosphate bioceramics are ideally suited for this purpose.
Chaudhry, Aqif Anwar
core
Hydrogen-bearing vesicles in space weathered lunar calcium-phosphates. [PDF]
Commun Earth Environ, 2023 Burgess KD, Cymes BA, Stroud RM.
europepmc +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source