Results 51 to 60 of about 1,516,700 (300)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Fosfatos de cálcio de interesse biológico: importância como biomateriais, propriedades e métodos de obtenção de recobrimentos Calcium phosphates of biological interest: importance as biomaterials, properties and methods for coatings obtaining

Química Nova, 2010
For decades the Hydroxyapatite (HA) was only bioceramic of calcium phosphate system used for bone replacement and regeneration, due to its similarity to the mineral phase of bones and teeth.
Antonio Carlos Guastaldi, Anahi Herrera Aparecida   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Immobilization of cesium from aqueous solution using nanoparticles of synthetic calcium phosphates

Chemistry Central Journal, 2018
The particularities of cesium incorporation into synthetic calcium phosphates with either apatite or whitlockite-type structures were investigated using the sorption process from aqueous solution and further heating to 700 °C.
Oksana Livitska, Nataliia Strutynska, Kateryna Loza, Oleg Prymak, Yuriy Prylutskyy, Olha Livitska, Matthias Epple, Nikolai Slobodyanik   +7 more
doaj   +1 more source

Physical and chemical properties of cement based on calcium phosphate suspensions [PDF]

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2017
The effect of phase composition, concentration of calcium phosphates suspensions and polymer binder on the physicochemical properties of calcium phosphate cements is found. It has been established that the introduction of monetite and polymers (polyvinyl
O.N. Musskaya, V.K. Krut’ko, A.I. Kulak   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Secretion of Organic Acids by Phosphate Solubilizing Bacteria Isolated from Oxisols

Journal of Tropical Soils, 2009
Phosphorus availability is a major limiting for crop production. Bacterial solubilization of insoluble inorganic phosphate has been studied as a means of providing available phosphorus for crop production.
Irfan Dwidya Prijambada, Jaka Widada, Siti Kabirun, Donny Widianto   +3 more
doaj  

Elaboration biphasic calcium phosphate nanostructured powders

Boletín de la Sociedad Española de Cerámica y Vidrio, 2015
Nanostructured calcium phosphate and biphasic calcium phosphates have been studied and stand out as biomaterials for bone regeneration. This is due to the fact that thesebiomaterials present bioactivity and morphological, chemical and crystallographic ...
G.M.L. Dalmônico, D.F. Silva, P.F. Franczak, N.H.A. Camargo, M.A. Rodríguez   +4 more
doaj   +1 more source