Results 101 to 110 of about 22,997 (192)

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

ASK1‐Induced FGF21 Synthesis in the Liver Prevents Obesity in Mice

Obesity, Volume 34, Issue 8, Page 1635-1646, August 2026.
ABSTRACT Objective Fibroblast growth factor 21 (FGF21) is a stress‐induced hormone secreted by the liver. It has a beneficial role in the regulation of glucose and energy metabolism. Herein, we identify apoptosis signal regulating kinase 1 (ASK1) as an inducer of hepatic FGF21 synthesis.
Anne Goergen, Tenagne D. Challa, Carlos Villaroel‐Vicente, Marcela Borsigova, Pim P. van Krieken, Christian Wolfrum, Matthias Blüher, Stephan Wueest, Daniel Konrad   +8 more
wiley   +1 more source

Exploring Patients' Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial. [PDF]

Arthritis Care Res (Hoboken)
Pascart T, Norberciak L, Richette P, Robinet P, Pacaud A, Marchasson G, Rabin T, Luraschi H, Maciejasz P, Georgel AF, Latourte A, Ea HK, Ottaviani S, Jauffret C, Ducoulombier V.   +14 more
europepmc   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Clinical Images: Flail elbows: destructive calcium pyrophosphate crystal arthritis. [PDF]

ACR Open Rheumatol
Szlembarski S, Falaas K, Gertner E.
europepmc   +1 more source

Evolutionary history and recombination in the mitochondrial carrier SLC25 superfamily analyzed by similarities in the exon and transmembrane α‐helix sequences

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Mitochondrial carriers (MCs), which constitute a superfamily also called the solute carrier family 25 (SLC25), are characterized by conserved signature motif sequences and a six‐transmembrane α‐helical transporter domain. They transport a wide variety of substrates ranging from protons, inorganic ions, citric acid cycle intermediates, and ...
Magnus Monné, Daniela Valeria Miniero, Rosa Calvello, Antonia Cianciulli, Luigi Palmieri, Ferdinando Palmieri   +5 more
wiley   +1 more source

Development and internal-external cross-validation of a patient-reported definition for acute calcium pyrophosphate crystal arthritis. [PDF]

Rheumatology (Oxford)
Cipolletta E, Rozza D, Andres M, Ottaviani S, Pascart T, Calvo-Aranda E, Chiarvetto Peralta MV, Muto P, Calabuig I, Gómez-Sabater S, Caño R, Léger B, Pacaud A, Moscioni E, Bruno C, Caira V, Gómez-González C, Rosa JE, Nakafero G, Filippucci E, Abhishek A.   +20 more
europepmc   +1 more source

Long‐Distance Aeolian Dust Deposited on the Island of Crete (Greece): Detection, Characterization, and Provenance

Journal of Geophysical Research: Earth Surface, Volume 131, Issue 8, August 2026.
Abstract Long‐distance aeolian dust transport represents one of the largest sediment fluxes on Earth, with North Africa being a dominant source. The island of Crete in the Eastern Mediterranean lies within major transport pathways but remains underexplored regarding multi‐proxy fingerprinting of deposited dust.
S. Bitzan, C. L. Blanchet, S. Pichat, G. E. Christidis, K. Schepanski, F. Kirsten   +5 more
wiley   +1 more source

Accelerated Progression of Arthritis after Four-Corner Fusion in Patients with Calcium Pyrophosphate Deposition Disease. [PDF]

J Wrist Surg
Gullborg EJ, Hoy JF, Wysocki RW, Fernandez JJ, Cohen MS, Simcock XC.   +5 more
europepmc   +1 more source

Artificial exposure to herbivore‐induced volatile organic compounds reduces herbivory and modulates gene expression in potato plants

Journal of Applied Ecology, Volume 63, Issue 8, August 2026.
These findings provide strong mechanistic evidence for VOCs mediating pest resistance and suggest that exposure to herbivore‐induced, plant‐derived VOCs can enhance pest resistance in potato crops. These results might offer novel information for developing ecologically sustainable plant volatile‐based strategies for boosting protection against pests in
Lucía Martín‐Cacheda, Alessio Tei, Gregory Röder, Yolanda Arnaiz, Luis Abdala‐Roberts, Xoaquín Moreira   +5 more
wiley   +1 more source