Results 81 to 90 of about 1,613,222 (311)

Safety and efficacy of calcipotriene plus betamethasone dipropionate topical suspension in the treatment of extensive scalp psoriasis in adolescents ages 12 to 17 years. [PDF]

, 2014
The objective of this study was to assess the safety and efficacy of the fixed combination calcipotriene 0.005% plus betamethasone dipropionate 0.064% topical suspension in adolescents with extensive scalp psoriasis.
Eichenfield, Lawrence F, Ganslandt, Cecilia, Kurvits, Merle, Schlessinger, Joel   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dissolution Rates of Calcium Boluses and Their Effects on Serum Calcium in Dairy Cattle

Veterinary Medicine: Research and Reports, 2021
Walter Verhoef,1 Sjoert Zuidhof,2 Brenda Ralston,3 Joseph A Ross,4 Merle Olson5 1Bureau Vétérinaire de Richmond, Richmond, Quebec, Canada; 2Sjoert Zuidhof Consulting, Okotoks, Alberta, Canada; 3Alberta Agriculture and Forestry, Airdrie ...
Verhoef W, Zuidhof S, Ralston B, Ross JA, Olson M   +4 more
doaj  

Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible [PDF]

, 2008
The aminophospholipid phosphatidylserine (PS) is normally restricted to the inner leaflet of the plasma membrane. During certain cellular processes, including apoptosis, PS translocates to the outer leaflet and can be labeled with externally applied ...
Gale, Jonathan E, Goodyear, Richard J, Kros, Corné J, Ranatunga, Kishani M, Richardson, Guy P   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Regulation of mitochondrial permeability transition pore by PINK1 [PDF]

, 2012
Background: Loss-of-function mutations in PTEN-induced kinase 1 (PINK1) have been linked to familial Parkinson’s disease, but the underlying pathogenic mechanism remains unclear.
Caballero, Erica, Chan, David, Gautier, Clemente A., Glaime, Emilie, Núñez, Lucía, Shen, Jie, Song, Zhiyin, Villalobos, Carlos   +7 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Egg Shell and Oyster Shell Powder as Alternatives for Synthetic Phosphate: Effects on the Quality of Cooked Ground Pork Products

Food Science of Animal Resources, 2017
This study aimed to determine the optimal ratio of natural calcium powders (oyster shell and egg shell calcium) as synthetic phosphate replacers in pork products. Ground pork samples were subjected to six treatments, as follows: control (−) (no phosphate
Min Guk Cho, Su Min Bae, Jong Youn Jeong
doaj   +1 more source

Lithium induced hypercalcemia: an expert opinion and management algorithm

International Journal of Bipolar Disorders, 2022
Background Lithium is the gold standard prophylactic treatment for bipolar disorder. Most clinical practice guidelines recommend regular calcium assessments as part of monitoring lithium treatment, but easy-to-implement specific management strategies in ...
Zoltan Kovacs, Peter Vestergaard, Rasmus W. Licht, Sune P. V. Straszek, Anne Sofie Hansen, Allan H. Young, Anne Duffy, Bruno Müller-Oerlinghausen, Florian Seemueller, Gabriele Sani, Janusz Rubakowski, Josef Priller, Lars Vedel Kessing, Leonardo Tondo, Martin Alda, Mirko Manchia, Paul Grof, Phillip Ritter, Tomas Hajek, Ute Lewitzka, Veerle Bergink, Michael Bauer, René Ernst Nielsen   +22 more
doaj   +1 more source

Rheological characterization of the thermal gelation of cowpea protein isolates: Effect of pretreatments with high hydrostatic pressure or calcium addition [PDF]

, 2019
Pretreatments with high hydrostatic pressure (HHP) or calcium addition were assessed for thermal gelation of two cowpea protein isolates (protein extraction at pHs 8.0, standard (A8) or 10.0, pH-shifting-modified (A10).
Avanza, María Victoria, de Llamballerie, Marie, Peyrano, Felicitas, Speroni Aguirre, Francisco José   +3 more
core   +2 more sources