Results 71 to 80 of about 906,408 (267)

Transcriptomic and Functional Insights of Calcium Suppresses Grape Berry Cracking: Antioxidant Activation, ABA Pathway Modulation, and VITPL1-Mediated Cell Wall Stability

open access: yesInternational Journal of Fruit Science
Calcium treatments are effective in reducing grapevine berry cracking. However, the underlying mechanism of calcium on grapevine berry cracking is not well-known. This work aims to explore the potential molecular mechanism of calcium treatment regulating
Shi Hao   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Calcium electroporation induces tumor eradication, long-lasting immunity and cytokine responses in the CT26 colon cancer mouse model

open access: yesOncoImmunology, 2017
Electroporation is used in cancer treatment because of its ability to increase local cytotoxicity of e.g. bleomycin (electrochemotherapy) and calcium (calcium electroporation).
Hanne Falk   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical Approach to Hypocalcemia in Newborn Period and Infancy: Who Should Be Treated?

open access: yesInternational Journal of Pediatrics, 2019
Introduction. Hypocalcemia is a common metabolic problem in newborn period and infancy. There is consensus on the treatment of the symptomatic cases while the calcium level at which the treatment will be initiated and the treatment options are still ...
Dogus Vuralli
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

THE CLINICAL AND METABOLIC EFFECTS OF CALCITRIOL IN THE TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS

open access: yesThe Turkish Journal of Gastroenterology, 2000
Osteoporosis is the most common metabolic disease of bone whose management is controversial. To evaluate the efficacy and safety of calcitriol (1,25-dihydroxyvitamin DJ in postmenopausal osteoporosis, this prospective, randomized, one-year clinical ...
Güneş Yavuzer   +4 more
doaj  

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