Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Validation of Synthetic Megavoltage Computed Tomography (MVCT) for Dose Calculation in Radiotherapy Treatment Planning. [PDF]
Corso A +11 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The Hartree-Fock Exchange for Crystalline Systems: The Implementation with an (<i>All-Electron</i>) Gaussian-Type Basis Set and Numerical Evidence with Reference to Perovskites. [PDF]
Dovesi R +4 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Statistical Issues in the Oliceridine versus Sufentanil Trial for Elderly Thoracoscopic Surgery [Letter]. [PDF]
Xu D, Ma H, Hou D.
europepmc +1 more source
Determination of HU override for gold fiducial markers in proton therapy. [PDF]
Zhang X +9 more
europepmc +1 more source
The theoretical calculation with laparoscopic and 3D-MSCT validation of the volume measurement method for a gastric pouch in gastric bypass surgery. [PDF]
Ospanov O, Sultanov K.
europepmc +1 more source
Rega: A Platform for the Prediction of the Regioselectivity of C-H Functionalization Reactions. [PDF]
Walton PJ +5 more
europepmc +1 more source
Sample size calculation practices in original research articles of the Journal of Conservative Dentistry and Endodontics (2021-2025). [PDF]
Sánchez-Tito M.
europepmc +1 more source

