Results 281 to 290 of about 5,707,552 (346)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Automated calculation of background parenchymal enhancement as a biomarker of treatment responses and recurrence-free survival in breast cancer. [PDF]

Breast Cancer Res Treat
Zhu Y, Hadidchi R, Nguyen HQ, Hariharan S, Weiss J, Hou W, Chung C, Luu HM, Ragupathi S, Maldjian T, Duong TQ.   +10 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A Silicon Resonant Pressure Microsensor Based on Frequency-Ratio Measurement for High-Temperature Applications. [PDF]

Micromachines (Basel)
Tan Z, Ye P, Liu X, Xie B, Lu Y, Chen D, Wang J.   +6 more
europepmc   +1 more source

A model of optical pump-terahertz probe by ultrafast terahertz near-field microscopy. [PDF]

iScience
Zhang Z, Huang Z, Xu A, Li J, Li P, Cai J, Dai M, Nie T, El Moutaouakil A, Wu X.   +9 more
europepmc   +1 more source

Inhibition mechanisms of gas desorption and pressure inversion in water-bearing coal under stepwise decompression via volume expansion. [PDF]

Sci Rep
Cheng X, Wang Z, Song J, Cheng C, Yang B, Ma X, He K, Gao M.   +7 more
europepmc   +1 more source

Beam commissioning of a new compact scanned proton therapy system with four different dose calculation algorithms. [PDF]

J Appl Clin Med Phys
Tanokura R, Horita M, Matsumoto M, Miyahara A, Furukawa S, Ido Y, Matsumoto A, Ogawa S, Makino W, Matsui Y, Tominaga Y, Kato T, Fuwa N.   +12 more
europepmc   +1 more source

Generalizability of deep learning-based dose conversion model in proton beam therapy. [PDF]

J Appl Clin Med Phys
Kato R, Kadoya N, Kato T, Tozuka R, Ogawa S, Murakami M, Jingu K.   +6 more
europepmc   +1 more source

Evaluating the Psychometric Properties of the 7C Vaccination Readiness Scale: Evidence from Slovenia. [PDF]

Zdr Varst
Vrdelja M, Branilović S, Lamot M, Kirbiš A.   +3 more
europepmc   +1 more source

"Ultrasonic elastography-guided pleural biopsy <i>versus</i> traditional thoracic ultrasound-guided pleural biopsy for the diagnosis of pleural effusion: a multicentre, randomised trial." M. Deng, Y. Xia, X. Ye, <i>et al</i>. <i>Eur Respir J</i> 2025; 66: 2501062. [PDF]

Eur Respir J
europepmc   +1 more source