Results 91 to 100 of about 166,028,341 (301)
Calculus of variations and its application to division of forest land
The paper deals with an application of the least squares method (LSM) for the purposes of division and evaluation of land. This method can be used in all cases with redundant number of measurements, in this case of segments of plots.
M. Matějík
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
On Artin's braid group and polyconvexity in the calculus of variations [PDF]
Let Ω ⊂ 2 be a bounded Lipschitz domain and let F : Ω × 2×2 + −→ be a Carathèodory integrand such that F (x, ·) is polyconvex for L2-a.e. x ∈ Ω. Moreover assume that F is bounded from below and satisfies the condition F (x, ξ) ∞ as det ξ 0 for L2-
ALI TAHERI +2 more
core +1 more source
A Calculus of Mobile Resources
We introduce a calculus of Mobile Resources (MR) tailored for the design and analysis of systems containing mobile, possibly nested, computing devices that may have resource and access constraints, and which are not copyable nor modifiable per se.
Godskesen, J.Chr. +2 more
core +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The article examines the possibility of applying elements of the calculus of variations to determine the quasi-optimum distribution of production at the time in terms of stochastic.
Grzesiak Stefan
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Personal technology and the calculus [PDF]
The calculus has long been seen as the pinnacle of mathematical endeavour in secondary schools, and rightly so. For as long as most of can remember, algebra and calculus have formed the trunk of mathematics, without which students can progress no further.
Kissane, B.
core

