Results 251 to 260 of about 781,568 (391)

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

open access: yesCancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu   +12 more
wiley   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

open access: yesChemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida   +8 more
wiley   +1 more source

Birth of India's first cloned cattle and analysis of its health and reproduction status: A case study. [PDF]

open access: yesSci Rep
Selokar NL   +7 more
europepmc   +1 more source

Highly Sensitive and Disposable DNA‐Based Electrochemical Biosensor for Detection of Daunorubicin

open access: yesChemElectroChem, EarlyView.
Herin, a flower‐like porous MnO2‐modified pencil graphite electrode (MnO2‐PGE) is developed for the electrochemical determination of the anticancer drug daunorubicin and its interaction with dsDNA. The developed electrochemical nanobiosensor has some advantages, such as easy‐to‐handle, cost‐effective, portable, less time‐consuming assay and disposable.
Mukerrem Findik   +2 more
wiley   +1 more source

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