Results 21 to 30 of about 10,543 (208)

The Nature of Cell‐Penetrating Poly(disulfide)s

Angewandte Chemie, EarlyView.
The mode of action of cell‐penetrating poly(disulfide)s (CPDs) is elucidated to understand thiol‐mediated uptake (TMU) in general and guide future efforts to control cellular entry for chemicals delivery and pathogen defense. ABSTRACT Cell‐penetrating poly(disulfide)s (CPDs) are the most popular thiol‐mediated uptake (TMU) tools for delivering attached
Saidbakhrom Saidjalolov, Giacomo Renno, Yuheng Zhang, Michael Cognet, Justin Neuman, Andreas Hennig, Naomi Sakai, Stefan Matile   +7 more
wiley   +2 more sources

Study of IR spectra of thiacalix[4]arene with carboxyl and adamantyl groups [PDF]

E3S Web of Conferences, 2021
The IR spectra of p-(3-carboxy-1-adamantyl)thiacalix[4]arene (1) were studied. IR spectra of compound 1 do not contain bands of free hydroxyl groups. The νOH value at 3377 cm-1 signifies the formation of an intramolecular H-bond along the lower edge of ...
Furer Victor, Potapova Ludmila, Vatsouro Ivan, Kovalev Vladimir, Shokova Elvira   +4 more
doaj   +1 more source

Synthesis and the biological activity of bis-mefenamidocalixarene

Журнал органічної та фармацевтичної хімії, 2019
Aim. To develop the method for the synthesis of the conjugate of diaminocalix[4]arene with 2-(2,3-dimethylphenyl)aminobenzoic acid (mefenamic acid) – bis-mefenamidocalixarene, determine its structure and physicochemical properties and assess its anti ...
Nataliya M. Chalenko, Roman V. Rodik, Ganna O. Syrova   +2 more
doaj   +1 more source

Aggregation, Cytotoxicity and DNA Binding in a Series of Calix[4]arene Amphiphile Containing Aminotriazole Groups

Pharmaceuticals, 2023
The present work focuses on the study of the aggregation and complexing properties of calixarenes as potential DNA condensation agents for gene delivery.
Diana Mironova, Egor Makarov, Islamiya Bilyukova, Kevser Akyol, Elsa Sultanova, Vladimir Evtugyn, Damir Davletshin, Elvina Gilyazova, Emil Bulatov, Vladimir Burilov, Svetlana Solovieva, Igor Antipin   +11 more
doaj   +1 more source

Crystal structure of tetraethyl 27,30-dioxo-7,12,20,25-tetra-tert-butyl-3,16-dioxa-9,22,28,31-tetrathiaheptacyclo[21.3.1.11,5.14,8.110,14.114,18.117,21]dotriaconta-4,6,8(29),10,12,17,19,21(32),23,25-decaene-2,2,15,15-tetracarboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The asymmetric unit of the title compound, C54H64O12S4, consists of one half of the molecule, which is located on an inversion centre. The heterocyclic six-membered ring adopts a distorted envelope conformation with the spiro C atom as the flap.
Mehmet Akkurt, Jerry P. Jasinski, Shaaban K. Mohamed, Omran A. Omran, Mustafa R. Albayati   +4 more
doaj   +1 more source

Azocalix[4]arene-Rhodamine Supramolecular Hypoxia-Sensitive Systems: A Search for the Best Calixarene Hosts and Rhodamine Guests

Molecules, 2021
A potential hypoxia-sensitive system host-guest complex of three calixarenes (including two with four anionic carboxyl and sulphonate azo fragments on the upper rim and a newly synthesized bis-azo adduct of calixarene in the cone configuration with azo ...
Diana Mironova, Vladimir Burilov, Farida Galieva, Mohamed Ali Mohamed Khalifa, Sofia Kleshnina, Alsu Gazalieva, Ramil Nugmanov, Svetlana Solovieva, Igor Antipin   +8 more
doaj   +1 more source

THE STRUCTURE OF THE TETRA-POTASSIUM SALT OF CALIX[4]ARENE DIHYDROXYPHOSPHONIC ACID [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2007
The solid-state structure of the tri-potassium calix[4]arene dihydroxyphosphonate salt is presented. In this structure, two potassium cations bridge between layers of dimeric calixarene diphosphonate units and two other potassium cations bridge along the
Adina N. Lazar, Oksana Danylyuk, Kinga Suwinska , Anthony W. Coleman   +3 more
doaj  

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

Advanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu, Xue Yuan, Yan Zhou, Rui Yuan, Shaocheng Xie, Yong Chen, Peiyi Wang, Jianmei Gao, Qihai Gong   +8 more
wiley   +1 more source

Research towards novel immunotherapeutic vectors: calixarene scaffolds [PDF]

, 2011
The aim of this project was to generate a new type of therapeutic delivery system and immunogenic vector, based on calixarenes, that is able to not only deliver immunogenic peptide but also act as a potential cancer vaccine.
Funck, M
core  

N,N,N-Triethylethanaminium 5,11,17,23-tetra-tert-butyl-25-[(ethoxycarbonyl)methoxy]-26,28-dihydroxy-27-oxido-2,8,14,20-tetrathiacalix[4]arene: a molecular salt

IUCrData, 2016
In the title molecular salt, C8H20N+·C44H53O6S4−, the conformation of the anionic tetrathiacalix[4]arene, which is cone-shaped, is primarily determined by intramolecular O—H...O hydrogen bonds.
Joel T. Mague, Mehmet Akkurt, Shaaban K. Mohamed, Omran A. Omran, Mustafa R. Albayati   +4 more
doaj   +1 more source