Results 111 to 120 of about 160,862 (306)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Enhanced caloric effect induced by magnetoelastic coupling in NiMnGaCu Heusler alloys: Experimental study and theoretical analysis

, 2017
On the basis of a phenomenological Landau model combined with comprehensive experimental studies, the magnetostructural transition behavior and field induced caloric effects for NiMnGaCu Heusler alloys have been investigated.
Zhao, Dewei, Planes, Antoni, Castan, Teresa, Liu, Jian, Sun, Wen, Li, Zongbin   +5 more
core  

Caloric Restriction Timecourse Project

Study investigating if the metabolic and skeletal effects of caloric restriction, in mice, depend on the duration of caloric ...
William Peter Cawthorn
core   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Longitudinal analysis of caloric requirements in critically ill trauma patients: a retrospective cohort study. [PDF]

PURPOSE Nutrition is of paramount importance in critically ill trauma patients. However, adequate supply is difficult to achieve, as caloric requirements are unknown.
Candinas, Daniel, Köhn, Nastassja, Hänggi, Matthias, Jakob, Dominik A, Haltmeier, Tobias, Magyar, Christian Tibor Josef, Schnüriger, Beat   +6 more
core   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Non-linear response of plant caloric value to N addition and mowing treatments in a meadow steppe

Ecological Processes
Background Caloric value is an important indicator of grassland ecosystem function, but the response of caloric value to nitrogen (N) addition and mowing is still unclear.
Jiaqi Ye, Shuai Wu, Yu Mo, Siqi Yang, Yu Zhao, Jing Zhang, Xiaotao Lü, Guojiao Yang, Xingguo Han, Cunzhu Liang, Zhenghai Li, Yajing Bao   +11 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

COMPARATIVE STUDY OF NUTRITIONAL INTAKE AND OPTIMUM NUTRITIONAL REQUIREMENTS IN PEDIATRIC INTENSIVE CARE OF A TERTIARY CARE HOSPITAL IN RAWALPINDI

Pakistan Armed Forces Medical Journal, 2017
Objective: To compare the difference in caloric and protein intake versus optimum protein and caloric requirements at pediatric ITC of AFIC. To see the difference in protein and caloric intake in patients on oral intake versus nasogastric feeding ...
Nabeela Fazal Babar, Iftikhar Ahmed, Sabat Babar, Hafsa Khalil   +3 more
doaj   +2 more sources

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source