Results 71 to 80 of about 270,797 (333)

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Effect of Caloric Restriction on Hepatic Sinusoidal System and Stellate Cells in Mice

open access: yesJournal of Aging Research, 2014
Aging associated changes in liver include reduced hepatic blood flow, increased number of stellate cells, and collagen deposits in perisinusoidal space. We tested the possibility of mitigating these changes with caloric restriction.
Jian Chen, Kara King, Jian X. Zhang
doaj   +1 more source

Microscopic systems with and without Coulomb interaction, fragmentation and phase transitions in finite nuclei [PDF]

open access: yes, 2001
We test the influence of the Coulomb interaction on the thermodynamic and cluster generation properties of a system of classical particles described by different lattice models. Numerical simulations show that the Coulomb interaction produces essentially
Carmona, J. M., Richert, J., Wagner, P.
core   +4 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Low caloric value of ethanol itself increases alveolar bone loss in ligature-induced periodontitis in male rats

open access: yesBrazilian Oral Research, 2009
This study aimed at morphometrically evaluating the influence of variable caloric values of ethanol consumption on alveolar bone loss in periodontitis in male rats. Thirty-six male rats were randomized into four groups of nine rats each, as follows: Test
Daniela Martins de Souza   +1 more
doaj   +1 more source

A threshold caloric test- results in normal subjects [PDF]

open access: yes
Threshold caloric test on normal subjects - responses to hot and cold caloric ...
Mc Leod, M. E., Meek, J. C.
core   +1 more source

Magneto-caloric effect in the pseudo-binary intermetallic YPrFe17 compound [PDF]

open access: yes, 2011
We have synthesized the intermetallic YPrFe17 compound by arc-melting. X-ray and neutron powder diffraction show that the crystal structure is rhombohedral with View the MathML source space group (Th2Zn17-type). The investigated compound exhibits a broad
Alvarez   +47 more
core   +2 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Sensitivity of caloric test and video head impulse as screening test for chronic vestibular complaints

open access: yesClinics
OBJECTIVE: This study compared the results of the caloric test with those of the video head impulse test obtained during the same session and evaluated whether the former can be used to screen for non-acute vestibular dysfunction.
Raquel Mezzalira   +4 more
doaj   +1 more source

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