Results 51 to 60 of about 260,179 (301)

Behavioural changes are a major contributing factor in the reduction of sarcopenia in calorie-restricted ageing mice [PDF]

, 2015
Background: In rodent models, caloric restriction (CR) with maintenance of adequate micronutrient supply has been reported to increase lifespan and to reduce age-induced muscle loss (sarcopenia) during ageing.
Anker, Argentino, Arnal, Austad, Bales, Boily, Boirie, Bool, Bouillanne, Campbell, Cano, Cava, Chen, Collins, Corhay, Cruz-Jentoft, Cuervo, Dwarkasing, Evans, Gallardo, Greenwood, Haehling, Harper, Lemon, Li, Loos, Luby, McKiernan, Michan, Miller, Mischke, Morris, Norren, Norren, Patel, Sandri, Santa Mina, Sanz, Scharf, Severinsen, Simpson, Speakman, Tieland, Walrand, Walrand   +44 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Calorie restriction regime enhances physical performance of trained athletes

Journal of the International Society of Sports Nutrition, 2018
Background Caloric restriction induces mitochondrial biogenesis and improves physical fitness in rodents. We aimed to provide evidence of how caloric restriction affects the body composition and physical performance of trained athletes and to evaluate ...
Victoria Pons, Joan Riera, Xavier Capó, Miquel Martorell, Antoni Sureda, Josep A. Tur, Franchek Drobnic, Antoni Pons   +7 more
doaj   +1 more source

Clinical Nutritional Study of Minimum Protein and Caloric Requirements for Man. Annual Report, Sep. 1965 - Sep. 1966 [PDF]

, 1966
Minimum protein and caloric requirements for prolonged manned spaceflight and space ...
Calloway, D. H., Margen, S.
core   +1 more source

Caloric curve of star clusters

, 2012
Self-gravitating systems, like globular clusters or elliptical galaxies, are the prototypes of many-body systems with long-range interactions, and should be the natural arena where to test theoretical predictions on the statistical behaviour of long ...
Casetti, Lapo, Nardini, Cesare
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Critical energy deficit and mortality in critically ill patients

Nutrición Hospitalaria
Objective: We investigate the influence of caloric and protein deficit on mortality and length of hospital stay of critically ill patients. Methods: A cohort prospective study including 100 consecutive patients in a tertiary intensive care unit (ICU ...
Marcia Carolina Siqueira-Paese, Diana Borges Dock-Nascimento, José Eduardo de Aguilar-Nascimento   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Caloric beverage consumption patterns in Mexican children

Nutrition Journal, 2010
Background Mexico has seen a very steep increase in child obesity level. Little is known about caloric beverage intake in this country as well as all other countries outside a few high income countries.
Rivera Juan A, Hernández-Barrera Lucia, Bonvecchio Anabelle, Campirano Fabricio, Barquera Simon, Popkin Barry M   +5 more
doaj   +1 more source