Caloric restriction and its mimetics [PDF]
BMB Reports, 2013 Caloric restriction is the most reliable intervention to preventage-related disorders and extend lifespan. The reduction ofcalories by 10-30% compared to an ad libitum diet is known toextend the longevity of various species from yeast to rodents.The ...
Shin-Hae Lee, Kyung-Jin Min
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Hepatic metabolic reprogramming in male mice during short-term caloric restriction involves enhanced glucocorticoid rhythms [PDF]
Nature CommunicationsCaloric restriction prolongs lifespan and preserves health across species, with feeding times synchronized to day–night cycles further maximizing benefits. However, the mechanisms linking diet, diurnal rhythms, and lifespan remain unclear.
Konstantinos Makris +14 more
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Effect of 8 weeks high-intensity interval training (HIIT) with and without caloric restriction on gene expression of myocardial Bax and Bcl2 in mice [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2021 Background: Apoptosis is the physiological cell death that in natural conditions leads to the elimination of old, damaged, waste, and harmful cells. The aim of this study was the effect of eight weeks of high-intensity interval training (HIIT) with and ...
Mohammadreza Zarali +3 more
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Unlocking the Potential: Caloric Restriction, Caloric Restriction Mimetics, and Their Impact on Cancer Prevention and Treatment [PDF]
MetabolitesCaloric restriction (CR) and its related alternatives have been shown to be the only interventions capable of extending lifespan and decreasing the risk of cancer, along with a reduction in burden in pre-clinical trials.
Ulises Edgardo De-Leon-Covarrubias +8 more
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The effect of eight weeks of high-intensity interval training with caloric restriction and spirulina supplementation on inflammatory factors in heart tissue of rats under high-fat diet [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2023 Background and Purpose: The increase of inflammatory factors following obesity is known as one of the main causes of mortality. Although the role of exercise training, caloric restriction and antioxidant supplements have been reported in this field; But ...
Jamshid Khirabadi +3 more
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Beneficial effects of intermittent fasting: a narrative review [PDF]
Journal of Yeungnam Medical Science, 2023 Caloric restriction is a popular approach to treat obesity and its associated chronic illnesses but is difficult to maintain for a long time. Intermittent fasting is an alternative and easily applicable dietary intervention for caloric restriction ...
Dae-Kyu Song, Yong-Woon Kim
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Caloric restriction decreases orthostatic tolerance independently from 6° head-down bedrest. [PDF]
PLoS ONE, 2015 Astronauts consume fewer calories during spaceflight and return to earth with an increased risk of orthostatic intolerance. Whether a caloric deficiency modifies orthostatic responses is not understood.
John P Florian +3 more
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Caloric restriction in humans [PDF]
Experimental Gerontology, 2007 Studies on mice and rats have demonstrated that calorie restriction (CR) slows primary aging, has a protective effect against secondary aging, and markedly decreases the incidence of malignancies. However, the only way to determine whether CR "works" in humans is to conduct studies on people. Such studies are difficult to perform in free-living people.
Holloszy JO, FONTANA, Luigi
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Journal of Animal Science and Technology, 2022 We aimed to investigate candidate proteins related to long-term caloric restriction and feed efficiency in bovine longissimus dorsi muscle (LM). A total of 31 Korean native steers were randomly distributed to ad
Usuk Jung +5 more
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The Potential of Fasting and Caloric Restriction to Mitigate Radiation Damage—A Systematic Review
Frontiers in Nutrition, 2020 Detrimental health effects from ionizing radiation to living organisms is one of the key concerns identified and addressed by Radiation Protection institutions, nationally and internationally on Earth and for human spaceflight.
Simon Valayer +14 more
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