Results 11 to 20 of about 844,015 (339)

Effect of the glucagon‐like peptide‐1 receptor agonist liraglutide, compared to caloric restriction, on appetite, dietary intake, body fat distribution and cardiometabolic biomarkers: A randomized trial in adults with obesity and prediabetes

Diabetes, obesity and metabolism, 2023
To investigate the hypothesis that weight loss with the glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) liraglutide alone would lead to a greater reduction in the proportion of fat to lean tissue mass when compared to caloric restriction (CR) alone ...
H. Silver, Dianna Olson, Dustin Mayfield, P. Wright, H. Nian, M. Mashayekhi, J. Koethe, K. Niswender, J. M. Luther, N. Brown   +9 more
semanticscholar   +1 more source

Dose–response effects of exercise and caloric restriction on visceral adiposity in overweight and obese adults: a systematic review and meta-analysis of randomised controlled trials

British Journal of Sports Medicine, 2023
Objective To determine and compare the dose–response effects of exercise and caloric restriction on visceral adipose tissue in overweight and obese adults, while controlling for the weekly energy deficit induced by the interventions.
Francesco Recchia, C. K. Leung, A. Yu, Welton Leung, Danny J Yu, D. Y. Fong, David Montero, C. Lee, S. S. Wong, P. Siu   +9 more
semanticscholar   +1 more source

Treadmill training or caloric restriction delays aging-associated increase in urocortin 2-induced hyperthermia in middle-aged male Wistar rats. [PDF]

Sci Rep
Kovacs DK, Berta G, Kormos V, Gaszner B, Petervari E, Balasko M.   +5 more
europepmc   +3 more sources

Caloric restriction in humans reveals immunometabolic regulators of health span

Science, 2022
The extension of life span driven by 40% caloric restriction (CR) in rodents causes trade-offs in growth, reproduction, and immune defense that make it difficult to identify therapeutically relevant CR-mimetic targets.
O. Spadaro, Y. Youm, I. Shchukina, S. Ryu, S. Sidorov, A. Ravussin, K. Nguyen, E. Aladyeva, A. Predeus, S. Smith, E. Ravussin, C. Galbán, M. Artyomov, V. Dixit   +13 more
semanticscholar   +1 more source

Caloric restriction induced epigenetic effects on aging

Frontiers in Cell and Developmental Biology, 2023
Aging is the subject of many studies, facilitating the discovery of many interventions. Epigenetic influences numerous life processes by regulating gene expression and also plays a crucial role in aging regulation.
J. Zhai, William H. Kongsberg, Yinbo Pan, Canhua Hao, Xiao-jing Wang, Jie Sun   +5 more
semanticscholar   +1 more source

Early time‐restricted eating compared with daily caloric restriction: A randomized trial in adults with obesity

Obesity, 2022
This trial aimed to evaluate the acceptability and efficacy of early time‐restricted eating plus daily caloric restriction (E‐TRE+DCR) compared with DCR alone within a behavioral weight‐loss intervention.
Elizabeth A Thomas, A. Zaman, K. J. Sloggett, Sheila C. Steinke, L. Grau, Victoria A Catenacci, M. Cornier, C. Rynders   +7 more
semanticscholar   +1 more source

Effects of caloric restriction on the gut microbiome are linked with immune senescence

Microbiome, 2022
Background Caloric restriction can delay the development of metabolic diseases ranging from insulin resistance to type 2 diabetes and is linked to both changes in the composition and metabolic function of the gut microbiota and immunological consequences.
J. Sbierski-Kind, Sophia Grenkowitz, S. Schlickeiser, A. Sandforth, M. Friedrich, D. Kunkel, R. Glauben, S. Brachs, K. Mai, Andrea Thürmer, A. Radonic, O. Drechsel, P. Turnbaugh, J. Bisanz, H. Volk, J. Spranger, Reiner Jumpertz von Schwartzenberg   +16 more
semanticscholar   +1 more source

Caloric restriction decreases orthostatic tolerance independently from 6° head-down bedrest. [PDF]

PLoS ONE, 2015
Astronauts consume fewer calories during spaceflight and return to earth with an increased risk of orthostatic intolerance. Whether a caloric deficiency modifies orthostatic responses is not understood.
John P Florian, Friedhelm J Baisch, Martina Heer, James A Pawelczyk   +3 more
doaj   +1 more source

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application

EMBO Molecular Medicine, 2021
Age‐associated diseases are rising to pandemic proportions, exposing the need for efficient and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and physiological levels. While nutrition and health are closely intertwined,
Sebastian J. Hofer, D. Carmona‐Gutierrez, Melanie I Mueller, F. Madeo   +3 more
semanticscholar   +1 more source

The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

bioRxiv, 2022
Caloric restriction (CR) is a nutritional intervention that reduces the risk of age-related diseases in numerous species, including humans. CR’s metabolic effects, including decreased fat mass and improved insulin sensitivity, play an important role in ...
K. Suchacki, Benjamin J. Thomas, Y. Ikushima, Kuang-Chan Chen, C. Fyfe, A. Tavares, Richard J. Sulston, Andrea Lovdel, Holly J. Woodward, Xuan Han, Domenico Mattiucci, E. Brain, C. Alcaide-Corral, Hiroshi Kobayashi, Gillian Gray, P. Whitfield, R. Stimson, N. Morton, A. Johnstone, W. Cawthorn   +19 more
semanticscholar   +1 more source