Results 31 to 40 of about 384,773 (212)

NADH/NAD⁺ Redox Imbalance and Diabetic Kidney Disease

Biomolecules, 2021
Diabetic kidney disease (DKD) is a common and severe complication of diabetes mellitus. If left untreated, DKD can advance to end stage renal disease that requires either dialysis or kidney replacement. While numerous mechanisms underlie the pathogenesis
Liang-Jun Yan
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Metabolic and behavioral compensations in response to caloric restriction: Implications for the maintenance of weight loss [PDF]

, 2009
BackgroundMetabolic and behavioral adaptations to caloric restriction (CR) in free-living conditions have not yet been objectively measured.Methodology and principal findingsForty-eight (36.8+/-1.0 y), overweight (BMI 27.8+/-0.7 kg/m(2)) participants ...
Eric Ravussin, Ravussin, E., Corby K. Martin, Leanne M Redman, Heilbronn, L., Corby K Martin, James P. Delany, Lilian de Jonge, Leonie K Heilbronn, Donald A Williamson, James P Delany, de Jonge, L., DeLany, J., Redman, L., Leanne M. Redman, null null, Martin, C., Pennington CALERIE Team, Williamson, D., Leonie K. Heilbronn, Donald A. Williamson   +20 more
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Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster [PDF]

, 2009
Background: Outcomes of lifespan studies in model organisms are particularly susceptible to variations in technical procedures. This is especially true of dietary restriction, which is implemented in many different ways among laboratories.
Linda Partridge, Partridge, L., Wong, Richard, Timothy M Bass, Partridge Linda, Grandison, R.C., Richard Wong, Wong, R., Tanimoto, H., Richard C Grandison, Bass, TM, Matthew D W Piper, Piper, M.D.W., Grandison, RC, Grandison, Richard C., Partridge, Linda, Wong, R, Bass Timothy M., Piper, MDW, Piper Matthew D. W., Partridge, L, Grandison Richard C., Bass, Timothy M., Piper, M. D W, Wong Richard, Bass, T.M.   +25 more
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Effects of caloric restriction on immunosurveillance, microbiota and cancer cell phenotype: Possible implications for cancer treatment

, 2020
Fasting, caloric restriction and foods or compounds mimicking the biological effects of caloric restriction, known as caloric restriction mimetics, have been associated with a lower risk of age-related diseases, including cardiovascular diseases, cancer ...
Battino M., Cianciosi D., Giampieri F., Iglesias R. C., Dominguez I., Pistollato F., Forbes-Hernandez T. Y., Quiles J. L., Ruiz R., Elexpuru Zabaleta M.   +9 more
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Caloric restriction mimetics for the treatment of cardiovascular diseases

, 2020
Caloric restriction mimetics (CRMs) are emerging as potential therapeutic agents for the treatment of cardiovascular diseases. CRMs include natural and synthetic compounds able to inhibit protein acetyltransferases, to interfere with acetyl coenzyme A ...
Forte, M, Sadoshima, J, Forte, Maurizio, Sadoshima, Junichi, Frati, Giacomo, Kroemer, G, Castoldi, F,, Versaci, Francesco, Castoldi, Francesca, Frati, G, Sciarretta, Sebastiano, Versaci, F, Maiuri, Maria Chiara, Kroemer, Guido, Sciarretta, S, Maiuri, MC   +15 more
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Advances in pharmacological interventions of aging in mice

Translational Medicine of Aging, 2019
The remarkable breakthroughs in aging research pave the way allowing us to explore potential interventions to slow down aging process, and more importantly, to improve healthiness.
Minxian Qian, Baohua Liu
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Antidiabeticheskiy biguanid metforminkak geroprotektor i antikantserogen

Ожирение и метаболизм, 2011
Growth hormone (GH)/insulin-like growth factor 1 (IGF-1)/insulin, DAF-2 and insulin-receptor control life span in various species including human. It is possible that the life-prolonging effect of calorie restriction is due to a decrease in IGF-1 levels.

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Colon tumor promotion, is it a selection process? Effects of cholate, phytate, and food restriction in rats on proliferation and apoptosis in normal and aberrant crypts [PDF]

, 1997
Promotion would suppose the selection of initiated cells. We tested the selection of aberrant crypt cells by cholic acid, a colon cancer promoter, and the effect of protectors, phytate and food restriction.
Peiffer, Ginette, Denis E. Corpet, Sylviane Taché, Taché, Sylviane, Ginette Peiffer, Corpet, Denis E.   +5 more
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To fast, or not to fast before chemotherapy, that is the question

BMC Cancer, 2018
Fasting in disease prevention and treatment has recently become a popular topic, particularly in the context of oncology. Unfortunately, the growing attention paid by the media has created a background of speculations and ambiguous messages. The attitude
Riccardo Caccialanza, Emanuele Cereda, Francesco De Lorenzo, Gabriella Farina, Paolo Pedrazzoli, on behalf of the AIOM-SINPE-FAVO Working Group   +5 more
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The effect of complete caloric intake restriction on human body odour quality [PDF]

, 2019
Previous studies on various vertebrates have shown that quantity and quality of food intake affect odour attractiveness as perceived by potential mates. In humans, the quality of body odour is similarly affected by ingested foods, such as by variation in
Fialová, Jitka, Havlíček, Jan, Hoffmann, Rudolf, Roberts, S Craig   +3 more
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