Results 201 to 210 of about 12,935 (279)

Avoid Confusion! Does Survival Processing Shape the Spontaneous Use of Learning Strategies for Distinguishing Edible and Poisonous Mushroom Twins?

open access: yesTopics in Cognitive Science, EarlyView.
Abstract Hunter‐gatherers faced the survival threat of confusing edible mushrooms with their poisonous twins, imposing selection pressure on those who failed to detect subtle visual differences. Grounded in the ancestral priorities framework, which posits that the human mind is adapted to handle prehistoric challenges, we investigated whether humans ...
Roman Abel
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Astrocyte‐derived lactate enhances neuronal NMDA receptor (NMDAR) function and synaptic plasticity through a redox‐ and CaMKII‐dependent mechanism. Lactate enters neurons via monocarboxylate transporters (MCTs) and is oxidized by lactate dehydrogenase (LDH) to pyruvate, generating NADH and increasing the intracellular NADH/NAD ...
Hubert Fiumelli   +13 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

A high‐fat, high‐sugar diet impairs maternal metabolism throughout pregnancy and lactation in mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study examined the impact of a high‐fat, high‐sugar (HFHS) diet consumed before mating and throughout pregnancy and lactation on maternal metabolic adaptation and early offspring outcomes in mice. Compared with controls, HFHS‐fed dams showed greater adiposity, impaired glucose tolerance, altered fuel utilisation with higher ...
Stephanie E. O'Hara   +5 more
wiley   +1 more source

3N Agriculture: Growing the greenest tomorrow

open access: yesAgricultural &Environmental Letters, Volume 11, Issue 1, June 2026.
Abstract The global food system must confront the intertwined challenges of feeding a growing population, reversing environmental degradation, and improving nutrition. While past agricultural innovations improved yields, they often undermined sustainability and food quality. In response, we propose the 3N Agriculture framework—Net‐Zero, Nature‐Positive,
Damien J. Field   +2 more
wiley   +1 more source

Changes in out-of-home food purchasing following England’s calorie labelling regulations: a population-level controlled interrupted time series

open access: yes
Kalbus A   +11 more
europepmc   +1 more source

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