Results 181 to 190 of about 28,252 (277)

Production of the High Value Pharmaceutical Target, Human Granulocyte‐Colony Stimulating Factor, in Nicotiana benthamiana Is Improved by Co‐Expression of the Transcriptional Regulator of the Unfolded Protein Response, bZIP60

Plant Biotechnology Journal, EarlyView.
Nazgul Wagner, Konstantin Musiychuk, Stephen Tottey, Jukka Kervinen, Hong Bi, Stephen J. Streatfield, Rainer Fischer, Vidadi Yusibov   +7 more
wiley   +1 more source

Oligoprogressive renal cell carcinoma: What is the role of surgery?

BJU International, Volume 138, Issue 2, Page 219-228, August 2026.
Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re, William H.J. Ince, Leo Bickley, James P. Blackmur, Mouhamad H. Ismail, Justicia Kyeremeh, Teele Kuusk, Eva Mendes Serrao, James O. Jones, Grant D. Stewart   +9 more
wiley   +1 more source

The clinical ionizable lipid SM-102 enhances photochemical immunogenic cell death by verteporfin-conjugated liposomes and improves survival in vivo. [PDF]

Photochem Photobiol Sci
Shah N, Quaye MB, Sudula B, Kulkarni N, Upreti A, Malkoochi A, Aileni TR, Karambelkar K, Peterson A, Mahmoud D, Vadlamudi MS, Soma SR, Jones CN, Brekken RA, Obaid G.   +14 more
europepmc   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4799-4822, August 2026.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

The Dual Mechanism of Action of CO-005 Overcomes CD20 Resistance in Diffuse Large B-Cell Lymphoma. [PDF]

Immunotargets Ther
Matar S, Skah S, Moltu LEB, Åmellem Ø, Hagland HR, Hestdal K, Pettersen RD, Richartz N.   +7 more
europepmc   +1 more source

Physiology and Transcriptomics Reveal Divergent Strategies of Mycorrhiza‐Mediated Drought Adaptation in Poplar

Plant, Cell &Environment, Volume 49, Issue 8, Page 5078-5094, August 2026.
ABSTRACT Mycorrhizal symbiosis shapes plant growth and stress resilience. Here, we compared physiological and molecular responses of poplars (P. x canescens) colonised by Paxillus involutus (Pi) or Cenococcum geophilum (Cg) under control conditions, drought stress and recovery.
Huili Shi, Zhuchou Lu, Andrea Polle
wiley   +1 more source

Harnessing Cuproptosis for Antitumor Immunity: A Review of Current Evidence and Therapeutic Strategies. [PDF]

Mol Carcinog
Lu I, Zhang J, Chen X, Wang XJ.
europepmc   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, Volume 49, Issue 8, Page 5849-5865, August 2026.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

Calcium Buffering in Astrocytes and Its Relevance for Experimental Data Interpretation and Computational Modeling. [PDF]

J Neurochem
Lenk K, Zeug A, Müller FE.
europepmc   +1 more source

Activation of an adaptive antitumor immune response by the polymeric fluoropyrimidine CF10 involves TS/Top1 dual targeting. [PDF]

Biomed Pharmacother
Behl A, Young TM, Ma X, Cedrone E, Dobrovolskaia MA, Whitesides JF, Gmeiner WH.   +6 more
europepmc   +1 more source